Results 81 to 90 of about 357,927 (302)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Upcycling Used Garments to Recreate Sustainable Fashion Designs Treated by Soil Release Finishing [PDF]

, 2016
Upcycled garments can have that independent appeal. No matter whom the designer is or what styling options designers choose, these upcycled fashion garments and accessories are by nature one-of-a kind.
Abdelrahman, S. H. (Shimaa), Eladwi, M. M. (Maha), Fathy, H. H. (HebaAllah), Mahmoud, A. S. (Aya), Shaker, R. N. (Rania), Sharaf, S. M. (Sarah)   +5 more
core  

Dilemmas of Development and The Reconstruction of Fashion [PDF]

, 2015
Sustainable development by its nature appears elusive. It seems the more we try to capture and pin it down the more it moves away from us leading us into murkier waters and all manner of contradictions.
A Fuad-Luke, A Lurie, D Miller, D Miller, DGK Dissanayake, E Wilson, EF Schumacher, G Monbiot, G Simmel, JR Harvey, K Fletcher, LG Curwen, M Braungart, M Collin, P Boradkar, Papanek, R Barthes, R Chambers, W Sachs, Y Kawamura, Z Bauman, Z Bauman   +21 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Signaling sustainability in online fashion consumption: The role of credibility induced by certification labels

Cleaner and Responsible Consumption
In recent years, the fashion industry invested a reasonable amount of resources into sustainable processes and marketing. However, among consumers, questions persist about the credibility of sustainability communication in online fashion retail.
Barbara Behre, Verolien Cauberghe
doaj   +1 more source

Designing for Fast and Slow Circular Fashion Systems: Exploring Strategies for Multiple and Extended Product Cycles [PDF]

, 2015
: This paper reviews work conducted by practiced-based textile design researchers based at the University of the Arts London (UAL) who were part of the multi-disciplinary, Swedish-based Mistra Future Fashion research consortium between June 2011 – May ...
Earley, Rebecca, Goldsworthy, Kate
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Public understanding towards sustainable clothing and the supply chain [PDF]

, 2011
The evident contradiction between fashion culture and sustainability raises critical issues for the clothing industry and public understanding will be important if strategies to help the industry evolve in a more sustainable direction are to succeed ...
Cooper, T, Knox, A, Saicheua, V
core  

Vivienne Westwood and the ethics of consuming fashion [PDF]

, 2016
Our paper examines ethical consumption using the case study of Vivienne Westwood, the fashion designer, and her eponymous firm, and shows how consumers of fashion might be considered ethical.
Agnew J. C., Atkinson P., Bordo S., Carnegy V., Charmaz K., Corley K. G., de Graaf J., Debord G., Evans C., Faurschou G., Gabriel Y., Geczy A., Geertz C., Gibson C., González A. M., Heath J., Holtzman B., Hoskins T., Krell G., Lunning F., Lydon J., McDermott C., Miles M. B., Miles M. B., Mulvagh J., Palomo-Lovinski N., Patton M. Q., Savage J., Silverman D., Silverman D., Simon M., Steele V., Vermorel F., Westwood V., Wilcox C., Yin R. K.   +35 more
core   +2 more sources