Results 61 to 70 of about 503,711 (309)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Sustainable housing development in post apartheid South Africa. [PDF]

open access: yes, 2011
The human settlement issue in South Africa has posed a great challenge to the post apartheid government. Due to apartheid, South African human settlements are characterised by spatial separation of residential areas according to class and race; urban ...
Ramashamole, Bokang
core  

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew   +11 more
wiley   +1 more source

Understanding how intertwined barriers and drivers shape energy community value propositions: A systematic literature review

open access: yesSustainable Futures
Value propositions, the reason for investment and involvement in certain projects, play a crucial role in attracting different actor groups to get involved in Energy Community (EC) projects.
Raúl Castaño-Rosa   +3 more
doaj   +1 more source

Sustainable Housing Development in Conditions of Changing Living Environment

open access: yesMATEC Web of Conferences, 2017
Article provides the organization-economic mechanism of sustainable development of the housing, the main content of which is formalized reflection of quality, environmental friendliness and cost of housing stock in conditions of changing living ...
Safronova Natalya   +2 more
doaj   +1 more source

Future Studies of Effective Factors on Sustainable Housing In Tehran Metropolitan [PDF]

open access: yesتوسعه پایدار شهری, 2021
In many developed countries, the change in attitudes towards planning types has been used to achieve the desired outcomes.One of the new attitudes toward the idea of planning is the futuristic approach which today is employed in both urban and housing ...
Zohreh Fanni   +2 more
doaj  

Formulating an Optimal Model for Designing and Assessing the Sustainable Housing Indices in Rural Areas (Case Study: Quchan Atigh Dehestan) [PDF]

open access: yesPizhūhish va barnāmah/rīzī-i rūstāyī, 2018
Purpose- sustainable rural housing can be considered as an important index in rural development. Hence, preparing plans in the area of sustainable rural housing requires different aspects and components of sustainable housing to be identified and ...
Hossein Farahani, Mehri Jahansoozi
doaj   +1 more source

Low-Quality Housing Is Associated With Increased Risk of Malaria Infection: A National Population-Based Study From the Low Transmission Setting of Swaziland. [PDF]

open access: yes, 2017
BackgroundLow-quality housing may confer risk of malaria infection, but evidence in low transmission settings is limited.MethodsTo examine the relationship between individual level housing quality and locally acquired infection in children and adults, a ...
Allen, Regan   +14 more
core   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

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