Results 21 to 30 of about 67,393 (264)
Sustainable libraries — fashion or necessity?
The article concerns a new libraries development strategy, which means taking account of the sustainable development concept in which the main emphasis is put on minimizing the negative influence on the natural environment, social and intergeneration justice.
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
This study was conducted to determine the factors influencing the adoption of green libraries for environmental sustainability, to find out the impacts and challenges faced by the librarians to adopt green libraries. For the systematic literature review,
Tariq Muhammad +2 more
doaj +1 more source
Recent Developments in Digital Mathematics Libraries
The paper presents recent developments in the domain of digital mathematics libraries towards the envisioned 21st Century Global Library for Math ematics.
Jiří Rákosník +2 more
doaj +1 more source
The Lanchester Library — Building a Sustainable Library
The award winning Lanchester Library is the largest deep plan naturally ventilated building in Europe and has consistently delivered significant energy savings compared to air conditioned buildings. The article provides some background to the design and explains the sustainable features of the building as well as describing how flexibility was built ...
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The COVID-19 pandemic and its associated response measures have profoundly impacted both the environment and human life, posing significant challenges to the achievement of the Sustainable Development Goals (SDGs). Several studies have utilized satellite
Xuejuan Chen, Zheping Xu, Tian Jiang
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Sustainability 3.0 in Libraries: A Challenge for Management
This article works on the three questions: “How can libraries make an effective contribution to resolving the sustainability challenges we are collectively facing?”; “When are libraries truly sustainable?”; and “How can library management support this shift?”.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

