Results 111 to 120 of about 2,289,577 (287)

Sustainable development : the key to tackling health inequalities [PDF]

, 2012
In November 2008, Professor Sir Michael Marmot was asked to advise the Secretary of State for Health on the future development of a health inequalities strategy in England post-2010.
Sustainable Development Commission
core   +1 more source

Factors influencing intimate partner controlling behaviour against rural women in South Africa

BMC Public Health
Background The widespread issue of gender-based violence (GBV) in South Africa profoundly affects various aspects of life, necessitating government intervention for prevention.
Oluwaseun T. Ojogiwa, Lanre Abdul-Rasheed Sulaiman, Moshood Issah   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Goodbye to Projects? ¿ A livelihoods-grounded audit of the Agricultural Sector Programme Support (ASPS) in Tanzania [PDF]

, 2003
YesApproaches to projects and development have undergone considerable change in the last decade with significant policy shifts on governance, gender, poverty eradication, and environmental issues.
Kamuzora, Faustin
core   +2 more sources

Governance fragmentation and food security in South Africa’s Upper Umzimvubu River catchment: A network governance perspective

Dynamics of Rural Society Journal
The Upper uMzimvubu River catchment in South Africa’s Eastern Cape faces persistently low food productivity, driven by land degradation and the escalating impacts of climate change.
Betty Claire Mubangizi
doaj  

Inclusive business for sustainable livelihoods

Field Actions Science Reports, 2011
What are the links between business and development? And what is the business role and opportunity in addressing sustainability challenges of developing countries and emerging economies?
Virginie Bonnell, Filippo Veglio
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Government support for indigenous knowledge for sustainability in Southern Africa

South African Journal of Information Management
Background: Government support for the use of indigenous knowledge (IK) for sustainable livelihoods assists in the achievement of sustainable development goals (SDGs).
Inesisa Ncube, Josiline Chigwada, Patrick Ngulube, Jan R. Maluleka   +3 more
doaj   +1 more source