Results 81 to 90 of about 6,076,403 (347)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sustainable Living in Finland: Combating Climate Change in Everyday Life

, 2018
Finland aims to be a carbon-neutral society by the year 2050. We are interested to know on a general level how sustainable living materializes among Finnish people, what is the structure of a sustainable lifestyle in Finland and how do people reason ...
A. Salonen, Jani Siirilä, M. Valtonen
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Sustainable Living Factories for Next Generation Manufacturing

, 2018
To be profitable and to generate sustainable value for all stakeholders, next generation manufacturers must develop capabilities to rapidly and economically respond to changing market needs while at the same time minimizing adverse impacts on the ...
Y. Koren, Xiyan Gu, F. Badurdeen, I. S. Jawahir   +3 more
semanticscholar   +1 more source

Sustainable Design Process and Factors Considered for Product Service System [PDF]

, 2009
"Sustainability" is apparently reflected in corporate management and product development. Technology development and industrial revolution not only provide human beings luxury living quality but also causes global environmental problems and natural ...
Chuan-Ying Hsu, Jui-Che Tu
core  

Governance and sustainability in Glasgow: connecting symbolic capital and housing consumption to regeneration [PDF]

, 2008
To transcend a legacy of slum-living, paternalistic provision and urban decline, Glasgow City Council has endeavoured to transform the city's fortunes by a plethora of mechanisms that have at their core the establishment of sustainable communities ...
Amin, Atkinson, Bailey, Bourdieu, Bridge, Bruntland Commission, Cameron, Clapham, Communities Scotland, Cruikshank, Flint, Flint, Flint, Foucault, Foucault, Glasgow City Council, Glasgow City Council, Glasgow City Council, Glasgow City Council, Glasgow Housing Association, Kintrea, Lees, Lemke, McKee, Mooney, Mooney, OECD, Raco, Rose, Scottish Executive, Scottish Office, Shaw, Slater, Taylor, Webster   +34 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Developing a flipbook on environmental change topics to enhance students’ conceptual understanding of sustainable living

JPBI (Jurnal Pendidikan Biologi Indonesia)
Sustainable living is a concept that refers to minimizing negative impacts on the surrounding environment. This research aims to develop an e-module flipbook on environmental change topic to increase insight into the concept of sustainable living.
Miftah Nur Hanifah Rida, Umi Fatmawati, Puguh Karyanto, Lilis Kusumawati   +3 more
doaj   +1 more source