Results 81 to 90 of about 4,128,252 (233)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Carbon Resources ConversionThe enormous amount of solid waste generated annually necessitates a transition toward circular economy strategies, especially targeting solid wastes such as waste tires, plastics, and biomass.
Amani Hussein +5 more
doaj +1 more source
Energies, 2017 The transition of our current energy system from a fossil-based system to a system based on renewables is likely to be one of the most complex and long-term societal transitions in history.
Claudia R. Binder +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Sustainable development in government 2008 : challenges for government [PDF]
, 2012 Our seventh annual SDiG assessment found good overall progress by the UK Government, especially on targets for water, waste and travel, though reductions in carbon emissions from offices were still not on track.Publisher ...
Sustainable Development Commission
core +2 more sources
Research progress on electronic monitoring in tuna longline fisheries
Frontiers in Marine ScienceThis paper presents a systematic review of recent research advances and practical applications of electronic monitoring systems (EMS) in tuna longline fisheries, with the aim of addressing persistent challenges in fisheries monitoring, including limited ...
Bing Yan +9 more
doaj +1 more source
Energies, 2018 In this paper, we apply an indicator-based approach to measure the resilience of energy regions in transition to a case study region in Austria. The indicator-based approach allows to determine the resilience of the transition of regional energy systems ...
Romano Wyss +2 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source