Results 151 to 160 of about 10,577,795 (233)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Unveiling the influence of social network characteristics on sustainable performance in small and medium-sized enterprises: A dynamic capabilities perspective. [PDF]

PLoS One
Jiang T, Zhang Y, Chen G, Feng H, Gao H, Cui Q, Lan T, Zhang Y.   +7 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Retraction: A systematic review of barriers in adoption of environmental management accounting in Chinese SMEs for sustainable performance. [PDF]

Front Public Health
Frontiers Editorial Office.
europepmc   +1 more source

Assessing the Impact of Green Hiring on Sustainable Performance: Mediating Role of Green Performance Management and Compensation. [PDF]

Int J Environ Res Public Health, 2021
Martins JM, Martins JM, Aftab H, Mata MN, Majeed MU, Aslam S, Correia AB, Mata PN.   +7 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A SEM-ANN analysis to examine impact of artificial intelligence technologies on sustainable performance of SMEs. [PDF]

Sci Rep
Soomro RB, Al-Rahmi WM, Dahri NA, Almuqren L, Al-Mogren AS, Aldaijy A.   +5 more
europepmc   +1 more source

We must practice what we preach: a framework to promote well-being and sustainable performance in the public health workforce in the United States. [PDF]

J Public Health Policy, 2022
Jackson Preston P.
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Retraction: Linkages between knowledge management process and corporate sustainable performance of Chinese small and medium enterprises: mediating role of frugal innovation. [PDF]

Front Psychol
Frontiers Editorial Office.
europepmc   +1 more source