Results 121 to 130 of about 24,573 (313)

Sustainability and UK food policy 2000-2011

, 2012
A report on food, farming, sustainable consumption and production.Publisher ...
Sustainable Development Commission
core  

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Effects of Project Management Challenges on the Use of Sustainable Construction Materials: Evidence from Construction Industry Practitioners

Civil and Environmental Engineering
The transition of the construction industry to sustainability is often hindered by project management challenges that prevent the effective use of sustainable construction materials.
Mehmood Sadar Din Khalid, Ishak Md. Sayuti   +1 more
doaj   +1 more source

Evaluating the Effectiveness of Supply Chain Management Practices in Enhancing Sustainability, Compliance, and Efficiency of Procurement Processes Within Local Municipality

International Journal of Sustainability in Business and Economics
This study was undertaken to evaluate the effectiveness of Supply Chain Management (SCM) practices in enhancing sustainability, compliance, and efficiency of procurement processes within a Local Municipality. The study addresses persistent challenges of
Kabelo Josaiah Phahlamohlaka, Sabelo Mpungose   +1 more
doaj   +1 more source

INVESTMENT STRUCTURES FOR SUSTAINABLE PROCUREMENT ACROSS THE PUBLIC SECTOR [PDF]

What is the meaning of the sustainable development concept? “Sustainable development is development that meets the needs of the present without compromising the ability of future generations to meet their own needs”.Why is it necessary that a nation to ...
Teodora (MÃNÃILÃ) PÃDUCEL
core  

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Sustainable Public Procurement: Integrating Environmental Standards into Global Supply Chains

This review examines "Sustainable Public Procurement: Integrating Environmental Standards into Global Supply Chains," which explores how public procurement can be leveraged to advance sustainability goals and address environmental challenges.
Mutangili, Solomon Kyalo
core   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Sustainability and Sustainable International Public Procurement Law in Kenya

This paper examined sustainability and sustainable international public procurement law in Kenya, analyzing the integration of environmental, social, and economic sustainability principles within the country's procurement framework. Through comprehensive
Mutangili, Solomon Kyalo
core   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source