Results 41 to 50 of about 40,764 (307)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Sustainability of psychiatric rehabilitation: systematic review [PDF]

open access: yesEuropean Journal of Public Health, 2014
Background An increase in mental health disorders can be observed in industrialised countries. Comprehensive psychiatric rehabilitation is expected to improve health and, consequently, to lower the number of disability pensions due to psychiatric disorders.
B Piso, I Reinsperger
openaire   +1 more source

From accelerometer data to activity patterns in chronic pain: methodical reasoning is key

open access: yesFrontiers in Sports and Active Living
Activity pattern (AP) concepts are widely used in interdisciplinary chronic pain (CP) care. It is assumed that AP can be objectively measured with accelerometry, but previous results show inconsistencies which may be attributed to methodical choices ...
Annet Doomen   +10 more
doaj   +1 more source

Quantification of the inevitable: the influence of soil macrofauna on soil water movement in rehabilitated open-cut mined lands [PDF]

open access: yesSOIL, 2016
Recolonisation of soil by macrofauna (especially ants, termites and earthworms) in rehabilitated open-cut mine sites is inevitable and, in terms of habitat restoration and function, typically of great value.
S. Arnold, E. R. Williams
doaj   +1 more source

A Survey on Gamification for Health Rehabilitation Care: Applications, Opportunities, and Open Challenges

open access: yesInformation, 2021
Research trends in gamification have shown a significant diversity in various areas of e-health, particularly in addressing the issues of rehabilitation and physical activity.
Nooralisa Mohd Tuah   +3 more
doaj   +1 more source

Medical Rehabilitation in Natural Disasters: A Review

open access: yes, 2019
Objective: To present an evidence-based overview of the effectiveness of medical rehabilitation intervention in natural disaster survivors and outcomes that are affected.Data Sources: A literature search was conducted using medical and health science ...
Rathore, Farooq A.   +4 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Building's rehabilitation towards sustainable behaviour [PDF]

open access: yes, 2010
To achieve a sustainable building’s behaviour and preserve the environmental balance, three laws must be taken into account: (i) the resources’ consume must not be faster than the rate at which nature can restock them, (ii) the creation of systems that ...
Ramos, A.T.V.F.   +3 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Role of Urban Rehabilitation in Achieving Sustainability in Heritage Urban Area [PDF]

open access: yesERU Research Journal
Sustainable urban rehabilitation plays a vital role in preserving cultural heritage while addressing the evolving demands of modern cities. This study examines the intersection of heritage conservation and sustainable urban development, emphasizing the ...
Zeinab Chaarawi   +2 more
doaj   +1 more source

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