Results 91 to 100 of about 921,011 (290)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Prediction of Bus Arrival Times at Bus Stop
International Journal of Technology, 2017 Bus arrival time is very important to passengers, not only at the origin terminal but also at every stop. If there is no predicted arrival time at a stop, the headway designed should match the bus frequency at the stop. The uncertainty in bus arrival
Ruslawati Abdul Wahab +2 more
doaj +1 more source
Smarter choices ?changing the way we travel. Case study reports [PDF]
, 2004 This report accompanies the following volume:Cairns S, Sloman L, Newson C, Anable J, Kirkbride A and Goodwin P (2004)Smarter Choices ? Changing the Way We Travel.
Anable, J +5 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Future “greener” urban transport: accessible, mobile and resilient cities? [PDF]
, 2013 Geographers, amongst others, have been considering urban futures for some time now. They all try to conceptually understand what a “sustainable city” in Europe / the UK / globally might look like.
Kotter, Richard
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Advances in Materials Science and Engineering, 2015 Freeze-thaw (FT) cycles and moisture susceptibility are important factors influencing the geotechnical characteristics of soil-aggregates. Given the lack of published information on the behavior of cement-bitumen emulsion-treated base (CBETB) under ...
Mojtaba Shojaei Baghini +1 more
doaj +1 more source
The role and position of Airport City in the Supply Chain
Production Engineering Archives, 2020 In the past, it was enough for the airport to have a runway and a modest terminal. The development of air traffic has also increased customer requirements (passengers, airlines, etc.), which has affected the need for airport infrastructure development ...
Drljača Miroslav +3 more
doaj +1 more source
Discovery exhibition: using spatial treemaps in local authority decision making and reporting [PDF]
, 2010 At Leicestershire County Council we are using spatial treemaps to analyse labour markets and commuting behaviour. This novel visualization technique, presented at InfoVis 2008, has resulted in a number of insights and discoveries.
Beecham, R. +4 more
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source