Results 141 to 150 of about 921,011 (290)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Sustainable settlement development - Assessing the effects of state measuresin scenario analysis [PDF]
The underlying research project was sponsored by the German Federal Ministry of Education and Research (BMBF) in the funding programme “Research for the Reduction of Land Consumption and for Sustainable Land Management” (REFINA). REFINA is implemented by
Martin Distelkamp, Philip Ulrich
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Is there room for shared cars in Italy? Considerations from some recent experiences [PDF]
Car sharing is increasing its role worldwide as an alternative transport mode, that could contribute to a more sustainable urban mobility by reducing congestion and pollution.
Grimaldi, Raffaele, Laurino, Antonio
core +1 more source
Sustainable mobility at the EU level - and the new transport White Paper [PDF]
, 2011 The main messages of the paper in four points are the following: (1) The environmental target for 2050 (sixty percent emission decrease, oil dependence decrease) is a very progressive vision, clear target.
Fleischer, Tamás
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The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Water Issues: Contributing to the Success of the Eighteenth and Nineteenth Sessions of the Commission on Sustainable Development [PDF]
, 2010 This article is about the discussions held at the 16th session of the Commission on Sustainable Development and recognizes that Integrated Water Resources Management (IWRM) was the framework for the entire water sector and an essential tool for ...
core
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Identifying the Implications of most Warming Foods: A Pilot Analysis [PDF]
The new found popular interest in sustainable development is highly skewed towards areas that are politically visible, such as transport and in particular the evils of air travel.
Beale, Jo +5 more
core +1 more source