Results 101 to 110 of about 268,741 (315)

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

open access: yesAdvanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li   +7 more
wiley   +1 more source

Which Sternotomy Closure Method (Orthopaedic Wire or Suture) Is Recommended in Large Breed Dogs Undergoing a Median Sternotomy?

open access: yesVeterinary Evidence, 2018
PICO questionWhich sternotomy closure method (orthopaedic wire or suture) is recommended in large breed dogs undergoing a median sternotomy?Clinical bottom lineThe literature search revealed no clinical studies on large breed dogs comparing the clinical ...
Charlotte Howes, Guillaume Chanoit
doaj   +1 more source

Biomaterial suture Vicryl Plus reduces wound-related complications

open access: yes, 2018
Qian Zhang, Chao Zhang, Xuanyu Fang, Xu Luo, Jiwei Guo Southwest Hospital, The Third Military Medical University (Army Medical University), Chongqing, China Objective: To compare the wound-related complications following craniotomy in patients with ...
Fang X, Guo J, Luo X, Zhang C, Zhang Q
core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

open access: yesAdvanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan   +12 more
wiley   +1 more source

The Role of Cyanoacrylate after Mandibular Third Molar Surgery: A Single Center Study

open access: yesBioengineering
Background: The management of the surgical wound of partially impacted mandibular third molar surgery has a great impact on recovery as well as on food impact retention. The present study used clinical parameters and health-related quality of life (HRQL)
Stefano Parrini   +3 more
doaj   +1 more source

Hydrogel Sealant for Closure of Clear Corneal Incisions in Combined Glaucoma Procedures

open access: yesClinical Ophthalmology, 2022
Ryan D Machiele,1 Abhilash Guduru,2 Leon W Herndon2 1Department of Ophthalmology, University of North Carolina, Chapel Hill, NC, USA; 2Department of Ophthalmology, Duke University Medical Center, Durham, NC, USACorrespondence: Leon W Herndon, Department ...
Machiele RD, Guduru A, Herndon LW
doaj  

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun   +7 more
wiley   +1 more source

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