Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Medial patellofemoral ligament reconstruction with a synthetic polyester suture tape graft and knotless anchors: Five-year clinical and functional outcomes. [PDF]
Ebied WF +5 more
europepmc +1 more source
Biliary tract complications in orthotopic adult liver transplantation: Comparison of anastomotic complications with braided absorbable suture (polyglactin 910) versus a new monofilament absorbable suture (polyglyconate) [PDF]
Gordon, RD +8 more
core
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Comparison of Bacterial Adhesion on Two Different Suture Materials After Tooth Extraction in Women Receiving Antiresorptive Therapy: An Exploratory Clinical Study with Prospective Data Collection. [PDF]
Mölzer A +7 more
europepmc +1 more source
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan +12 more
wiley +1 more source
The application of single-hole laparoscopic repair with slow-absorbable suture in the treatment of indirect inguinal hernia in children. [PDF]
Wang C, Zheng Y, Feng Q.
europepmc +1 more source
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source
Dual-Action Sutures: Chlorhexidine and Dexamethasone for Infection Control and Inflammation Suppression. [PDF]
Hernández-Ramírez BG +10 more
europepmc +1 more source

