Results 131 to 140 of about 5,603,050 (250)

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

open access: yesAdvanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng   +8 more
wiley   +1 more source

Suture Block Model Photo Layout

open access: yes, 2018
"Suturing is one of the most commonly taught skills in surgery. This demand makes model durability one of the most important features. After trying multiple commercial models priced at $25/piece, we developed this low cost version from simple items.
Peter Bartline MD; Ruth Braga MSN; William Peche MD; Daniel Vargo MD
core  

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian   +21 more
wiley   +1 more source

Varying Distance Between Suture Buttons Does Not Improve Stability of the Transected Syndesmosis and Deltoid Ligament in a Motion-Tracking Cadaveric Model

open access: yesOrthopaedic Journal of Sports Medicine
Background: A growing body of evidence favors the use of dynamic fixation techniques such as suture button fixation over rigid screw fixation for syndesmotic injuries. However, specific dynamic fixation techniques have been poorly evaluated.
Taylor Stauffer MD   +9 more
doaj   +1 more source

Suture Block Model Ingredient List

open access: yes, 2018
"Suturing is one of the most commonly taught skills in surgery. This demand makes model durability one of the most important features. After trying multiple commercial models priced at $25/piece, we developed this low cost version from simple items.
Peter Bartline MD; Ruth Braga MSN; William Peche MD; Daniel Vargo MD
core  

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

An ex vivo evaluation of two different suture techniques for the Ozaki aortic neocuspidization procedure. [PDF]

open access: yesInteract Cardiovasc Thorac Surg, 2021
Saisho H   +6 more
europepmc   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou   +14 more
wiley   +1 more source

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