A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi +11 more
wiley +1 more source
A finite element study on three maxillary protraction devices for treating maxillary sagittal hypoplasia at different levels of bone fusion. [PDF]
Sun K +5 more
europepmc +1 more source
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li +8 more
wiley +1 more source
A giant bleb over a non-valved tube successfully treated with compression sutures. [PDF]
Fonseca M, Saini C, Margeta MA.
europepmc +1 more source
Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin +19 more
wiley +1 more source
Tensile Strength of Nylon Sutures Versus Polyglycolic Acid Sutures Immersed in Camu camu (<i>Myrciaria dubia</i>) and Tumbo (<i>Passiflora tripartita</i>) Juices: A Linear Regression Model. [PDF]
Mamani-Salinas T +6 more
europepmc +1 more source
Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
Mechanical performance of sutures exposed to natural extract-based mouthwashes. [PDF]
Alaqeely R +6 more
europepmc +1 more source
A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi +8 more
wiley +1 more source
An innovative `8'-shaped deep-layered suture method for incision suture rejection: a case report. [PDF]
Wang BY, Wang Z, Yuan M, Wang YC.
europepmc +1 more source

