Results 211 to 220 of about 371,392 (313)

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source

Asymptomatic Uterine Rupture in a Pregnancy Following B-Lynch Suture Application in a Previous Delivery: A Case Report. [PDF]

Clin Case Rep
Omran K, Mathew G, Shahin M, Omran O.
europepmc   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

Advancements in surgical modalities for corneal hydrops: A comprehensive review. [PDF]

J Int Med Res
Abtahi MA, Zeidabadinejad H, Aminizade M, Karaca EE, Tomaras N, Lee K, Soleimani M.   +6 more
europepmc   +1 more source

Table S2. Anatomy of two Permian greenschist- to blueschist-facies tectonic mélanges in the Solonker Suture Zone (Inner Mongolia, NE China): Evidences for divergent double subduction and soft collision

, 2020
Huichuan Liu, Jichun Wang, Chun‐Kit Lai, Yinglei Li, Jingfan Wang, Chongyu Song, Jiadong Zhang, Xin Zhao, Jiangdong Qin   +8 more
openalex   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Fine sutures combined with local flaps in the cosmetic repair of surgical defects of basal cell carcinoma of the head and face: a single-centre retrospective clinical study. [PDF]

Eur J Med Res
Chen H, Li Q, Zhe N, Huang N.
europepmc   +1 more source

Tracheal injuries cured without direct suturing: Report of two cases

, 2018
Toshihiro Ikeda, Tetsuhiko Go, Jun Nakano, T Okubo, Naoya Yokota, Hiroyasu Yokomise   +5 more
openalex   +2 more sources

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Beyond Sutures: Moist Exposed Burn Ointment (MEBO) and Scar Massage for Anatomical Restoration of Penetrating Upper Lip Laceration at the Vermilion-Cutaneous Junction in Primary Care-A Case Report. [PDF]

Clin Med Insights Case Rep
Abualadas HM.
europepmc   +1 more source