Results 261 to 270 of about 456,239 (386)

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Suture-based rib approximation for the repair of minimally invasive surgery-related lung hernia: a case series. [PDF]

J Surg Case Rep
Takahashi Y, Miyajima M, Maki R, Chiba Y, Ohyu T, Sato K, Honda K, Watanabe A.   +7 more
europepmc   +1 more source

VII. Practical Value of Secondary Wound-Suture [PDF]

, 1887
H HELFERIC
openalex   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Utilization of spectral filteration for ultra-low dose brain CT in pediatric patients for diagnosis of craniosynostosis: A phantom study. [PDF]

J Appl Clin Med Phys
Braniff C, Ditchfield M, Gubser M, Kuganesan A, Badawy MK.   +4 more
europepmc   +1 more source

A CASE OF PERFORATION OF THE RECTUM INTO THE PERITONEAL CAVITY ; LAPAROTOMY; SUTURE; RECOVERY. [PDF]

, 1902
G.R. Turner
openalex   +1 more source

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

Advanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu, Jin‐Yin Huang, Xing‐Zhe Xu, Ji‐Yu Sun, Dan‐Ni Zou, Jia‐Yao Zhang, Chen Chi, Qi Zhang, Wei‐Cai Liu   +8 more
wiley   +1 more source

Stahl's ear correction: A review of surgical approaches. [PDF]

JPRAS Open
Nassar A, Naba J, Eid D, Zeid SA, Demian J.   +4 more
europepmc   +1 more source

THE EFFECTS OF TEMPERATURE ON THE DIGESTION OF COLLAGEN SUTURES AND SURGICAL GUT (CATGUT) BY ENZYMES AND BY THE SUBCUTANEOUS TISSUES OF THE FROG

, 1945
Irwin W. Sizer
openalex   +2 more sources

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source