Influence of the Tendon Grasping Technique on Tensile Strength in 6-strand Sutures. [PDF]
Moriya K+4 more
europepmc +1 more source
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan+4 more
wiley +1 more source
A Comparative Study of Triclosan-Coated Suture Versus Conventional Suture on Surgical Site Infections of Abdominal Fascial Closures in Open Appendectomy. [PDF]
Doddannavar S+9 more
europepmc +1 more source
Bacteria Adhere Less to Barbed Monofilament Than Braided Sutures in a Contaminated Wound Model
J. Fowler+3 more
semanticscholar +1 more source
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen+12 more
wiley +1 more source
Clinical outcomes of xenogeneic acellular dermal matrix combined with full-thickness skin graft in the eyelid reconstruction following the excision of eyelid malignant tumors. [PDF]
Xie L, Xie J, Wang W.
europepmc +1 more source
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu+18 more
wiley +1 more source
Importance of the diameter of the mechanical suture in rectal surgery in relation to benign anastomotic stenosis. Cross-sectional observational study. [PDF]
Llorach-Perucho N+2 more
europepmc +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source