Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song +8 more
wiley +1 more source
Signal extraction in SWAXS data for the compact X-ray light sources: a machine learning approach. [PDF]
Opperman AK +8 more
europepmc +1 more source
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA) frequently co‐occurs with Alzheimer's disease (AD), generating mixed vascular–neurodegenerative phenotypes. Plasma phosphorylated tau (p‐tau)217 is a robust biomarker of AD, but its performance in CAA remains unclear. METHODS We studied 231 participants, including 50 patients with CAA (Boston v2.0)
Aida Fernández‐Lebrero +19 more
wiley +1 more source
Prevalence and Risk Factors for Cerebral Microbleeds in Chinese Patients With Acute Ischemic Stroke. [PDF]
Zhu R +5 more
europepmc +1 more source
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
Enhancing Recommendation Systems through SVD-based collaborative filtering and community detection. [PDF]
Keerthika T +6 more
europepmc +1 more source
Supervised Restricted Data Fusion With Common, Local, and Distinct Components
ABSTRACT In multi‐block data, the dominant sources of variation are not always most relevant to a response of interest, meaning that purely exploratory decompositions may fail to recover subtle but important response‐associated structure. We introduce PESCAR, a supervised extension of Penalised Exponential Simultaneous Component Analysis (PESCA) that ...
Fred T. G. White +6 more
wiley +1 more source
Benefit of selinexor dose reduction on outcomes with selinexor, bortezomib and dexamethasone in patients with lenalidomide-refractory multiple myeloma: Subgroup analysis of the BOSTON trial. [PDF]
Delimpasi S +8 more
europepmc +1 more source
ABSTRACT Introduction Violence against women is a major human rights violation and public health concern with serious physical, mental, sexual, and reproductive consequences. Intrapartum obstetric violence can damage trust in healthcare providers and discourage women from using facility‐based maternity services, sometimes more than geographic or ...
Mequanente Dagnaw +2 more
wiley +1 more source
The Therapeutic Potential of H2S‐Releasing Platforms in Cardiovascular Applications
The Therapeutic Potential of H2S‐Releasing Platforms. ABSTRACT Once known as a toxic gas, hydrogen sulfide (H2S) is now making its way into many therapeutic applications. Similar to its other fellow endogenous gasotransmitters, nitric oxide and carbon monoxide, H2S is a small gas with a short half‐life, making it extremely capable of penetrating ...
Tia N. Shorter, Elizabeth J. Brisbois
wiley +1 more source

