Results 51 to 60 of about 256 (160)

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

From observation to understanding: A multi‐agent framework for smart microscopy

Journal of Microscopy, EarlyView.
Abstract Smart microscopy represents a paradigm shift in biological imaging, moving from passive observation tools to active collaborators in scientific inquiry. Enabled by advances in automation, computational power, and artificial intelligence, these systems are now capable of adaptive decision‐making and real‐time experimental control.
P. S. Kesavan, Pontus Nordenfelt
wiley   +1 more source

Genomic Medicine Sweden: Advancing precision medicine at the national level

Journal of Internal Medicine, EarlyView.
Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö, Anna Lindstrand, Panagiotis Baliakas, David Gisselsson, Paula Mölling, Mia Wadelius, Åsa Johansson, Hannes Olauson, Hans Ehrencrona, Lovisa Lovmar, Christian G. Giske, Henrik Green, Ann Nordgren, Fulya Taylan, Martin Hallbeck, Erika Tång Hallbäck, Anna Green, Markus Heidenblad, Kina Höglund, Anders Jemt, Carl Mårten Lindqvist, Maria Johansson Soller, Magnus Sabel, Colum Walsh, Hartmut Vogt, Craig E. Wheelock, Martin Bergö, Jens Enoksson, Ann Ekberg Jansson, Cecilia Fagerström, Jan Holgersson, Stephanie Anja Juran, Mats G. Karlsson, Frida Lundmark, Eva Tiensuu Janson, Andreas Muranyi Scheutz, Malin Sund, Päivi Östling, Sofia Gruvberger‐Saal, Marene Landström, Malin Melin, Lars Palmqvist, Richard Palmqvist, Bianca Stenmark, Anna Wedell, Malin Karnå, Katarina Nyström, Tobias Strid, Per Sikora, Maria Johansson, Therese Fagerqvist, Mirja Carlsson Möller, Oskar Frisell, Mats Ulfendahl, Mikaela Friedman, Lucia Cavelier, Valtteri Wirta, Thoas Fioretos, Richard Rosenquist   +58 more
wiley   +1 more source

Placental malperfusion and angiogenesis‐related proteins are associated with small‐for‐gestational‐age in systemic lupus erythematosus

Journal of Internal Medicine, EarlyView.
Abstract Background Although systemic lupus erythematosus (SLE) pregnancy frequently results in small for gestational age (SGA) infants, the understanding of underlying mechanisms is limited. We aimed to identify specific histological patterns of placental injury in SGA in SLE and to explore whether an altered balance of angiogenesis‐related proteins ...
Marit Stockfelt, Henri Puttonen, Ing‐Marie Fyhr, Agnes Torell, Kerstin Andersson, Iva Gunnarsson, Elisabet Svenungsson, Agneta Zickert, Maria Majczuk Sennström, Estelle Trysberg, Anders A. Bengtsson, Andreas Jönsen, Helena Strevens, Christopher Sjöwall, Muna Saleh, Sofia Pihl, Dag Leonard, Lars Rönnblom, Tansim Akhter, Bo Jacobsson, Anna‐Carin Lundell, Anna Rudin   +21 more
wiley   +1 more source

Hypoglycaemia Was Not Associated With Depression, Anxiety, Diabetes Distress or Fear of Hypoglycaemia Scores in People With Type 1 or Insulin‐Treated Type 2 Diabetes in the Hypo‐METRICS Study

Diabetes, Obesity and Metabolism, EarlyView.
Aisling McCarthy, Uffe Søholm, Natalie Zaremba, François Pouwer, Allan A. Vaag, Simon Heller, Julia K. Mader, Ulrik Pedersen‐Bjergaard, Bastiaan E. de Galan, Eric Renard, Mark L. Evans, Rory J. McCrimmon, Stephanie A. Amiel, Pratik Choudhary, Patrick Divilly, Hypo‐RESOLVE Consortium   +15 more
wiley   +1 more source

Selective glomerular hypofiltration is associated with glucometabolic disturbances in the general population

Journal of Internal Medicine, EarlyView.
Abstract Background Discordance between cystatin C‐ and creatinine‐based estimated glomerular filtration rate (eGFR) has been linked to adverse outcomes. A low eGFRcys/eGFRcr‐ratio, conceptualized as selective glomerular hypofiltration syndrome (SGHS), has been hypothesized to reflect early metabolic kidney vulnerability, although non‐glomerular ...
Christopher Nilsson, Agne Laucyte‐Cibulskiene, Amra Jujic, Marcus A. Ohlsson, Gregor Guron, Maria K. Svensson, Maria Weiner, P. Andreas Jonsson, Johan Ärnlöv, Gunnar Engström, Anders Grubb, Anders Larsson, Martin Magnusson, Anders Christensson   +13 more
wiley   +1 more source

Changes in Nighttime Sleep Duration and Their Association With Cognitive Decline and Dementia Risk

Journal of Sleep Research, EarlyView.
ABSTRACT This study investigates changes in nighttime sleep duration in relation to cognitive decline and risk of incident dementia. A total of 3057 participants from the Swedish population study ‘Good Aging in Skåne’ (Mage = 68.4) with normal baseline sleep duration (6–8 h) were followed up to 20 years (Myears = 8.39). Self‐reported change was defined
Marieclaire Overton, Sölve Elmståhl, Rani Basna   +2 more
wiley   +1 more source

Dupilumab‐Induced Psoriasis in an Adolescent With Severe Atopic Dermatitis: Successful Management With Abrocitinib

Pediatric Dermatology, EarlyView.
ABSTRACT Psoriasiform eruptions have been described in patients treated with dupilumab. This case report describes an adolescent with severe atopic dermatitis who developed a widespread psoriasiform dermatitis 8 months after starting dupilumab. His therapy was switched to abrocitinib resulting in near‐complete resolution of the psoriatic lesions with ...
Grigorios Theodosiou, Åke Svensson
wiley   +1 more source

Choice of Growth Standard and Interpretation of Large for Gestational Age Outcomes: Evidence From the CDC4G Trial

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background The lack of a standardised definition of large for gestational age (LGA) complicates clinical assessments and the interpretation of research. Objective The objective of this study is to assess how different definitions of LGA affect the interpretation of outcomes in a stepped wedge cluster randomised controlled trial (SW‐CRT ...
Sara Grass, Maryam de Brun, Anders Magnuson, Martina Persson, Anna‐Karin Wikström, David Simmons, Snehal Patil, Verena Sengpiel, Scott Montgomery, Kerstin Berntorp, Ulla‐Britt Wennerholm, Helena Strevens, Karin Hildén, Elisabeth Storck‐Lindholm, Helena Backman, Fredrik Ahlsson   +15 more
wiley   +1 more source

An international study on emerging arboviral infections and blood safety

Transfusion, EarlyView.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra, Helen M. Faddy, Daniel Candotti, Carolina B. Bub, Jose M. Kutner, Steven J. Drews, Carmen L. Charlton, Sheila F. O'Brien, Wai‐Chiu Tsoi, Michel‐Andres Garcia‐Otalora, Claire Reynolds, Tuulia Palukka, Riikka Lehtisalo, Ruth Offergeld, Axel Seltsam, Marijke Weber‐Schehl, Nahid Chenarsabz, Naoko Goto, Sung‐Chan Park, So‐Yong Kwon, Ryanne Lieshout‐Krikke, Aneta Kopacz, Ewa Sulkowska, Oana‐Alexandra Șerban, Simona Ruta, Eugene Zhiburt, Maha Badawi, Josephine Mitchel, Ute Jentsch, Ángel Luis Pajares Herraiz, Ana Lafuente Guijosa, Gülşen Özkaya Şahin, Christoph Niederhauser, Marion C. Lanteri, Brian Custer, Galen Conti, Anthea Cheng, Shannah Secret, Peter Simmonds, Heli Harvala, on behalf of the Virology subgroup of the ISBT WP‐TTID   +40 more
wiley   +1 more source