Results 141 to 150 of about 242,314 (287)

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert   +6 more
wiley   +1 more source

Corrigendum: The effects of intermittent theta burst stimulation of the unilateral cerebellar hemisphere on swallowing-related brain regions in healthy subjects

open access: yesFrontiers in Human Neuroscience, 2023
Bingyan Wang   +6 more
doaj   +1 more source

‘It's all very well having a diverse curriculum, but if there is no curriculum, it can be as diverse as you like’: Precarity and decolonising in the neoliberal UK higher education system

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Drawing upon interview research across two academic departments as part of the early stages of a ‘decolonise the curriculum’ initiative at a Southern UK university, this study highlights a growing gulf between policy and practice in efforts to address systemic racial inequalities in UK universities. A reliance upon precarious labour, a culture
Triona Fitton   +4 more
wiley   +1 more source

Beyond mammals: the evolution of chewing and other forms of oropharyngeal food processing in vertebrates

open access: yesBiological Reviews, EarlyView.
ABSTRACT Oropharyngeal food processing exhibits a remarkable diversity among vertebrates, reflecting the evolution of specialised ‘processing centres’ associated with the mandibular, hyoid, and branchial arches. Although studies have detailed various food‐processing strategies and mechanisms across vertebrates, a coherent and comprehensive terminology ...
Daniel Schwarz   +6 more
wiley   +1 more source

Diet of bird‐like troodontid dinosaurs: synthesis of a contentious clade

open access: yesBiological Reviews, EarlyView.
ABSTRACT Troodontidae is a clade of small‐to medium‐sized maniraptoran theropods that mainly lived in Laurasia (modern Asia, North America and Europe) during the Jurassic and Cretaceous periods and are believed to have had a variety of diets. The uniqueness of troodontid teeth suggests that they diverged from the typical flesh‐based diet of non‐avian ...
Yui Chi Fan   +2 more
wiley   +1 more source

Corporate Management of Environmental, Social, and Governance Ratings and Rating Divergence

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT As environmental, social, and governance (ESG) ratings increasingly influence investment and corporate decision‐making, companies face growing pressure to manage their ESG performance strategically. This study examines how firms navigate the fragmented ESG rating landscape marked by significant agency divergence. Based on a multiple‐case study
Selina Hauch
wiley   +1 more source

Yutma ve Solunum İlişkisi: Genel Bilgiler

open access: yesDil, Konuşma ve Yutma Araştırmaları Dergisi, 2018
Yutma ve solunum arasında yakın bir ilişki vardır. Yutma ve solunumun birbirine yakın bölgede bulunan oromotor Central Pattern Generators (CPGs) tarafından düzenlenmeleri, benzer nöral yolları ve benzer oral-farengeal yapıları kullanmaları gibi ...
Cemil Yılmaz
doaj  

Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley   +1 more source

Profession‐Related Accreditation Requirements in Australia Regarding Anatomy Teaching: A Web‐Based Desktop Audit

open access: yesClinical Anatomy, EarlyView.
ABSTRACT For effective and safe practice, health professionals need an understanding of functional anatomy. Registration boards, councils or self‐regulating professional associations determine the standards, codes, graduate competencies and education program accreditation requirements which inform health curricula development and content.
Anita Zacharias   +5 more
wiley   +1 more source

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