Results 81 to 90 of about 6,755 (259)

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Pharyngeal pressure generation during tongue-hold swallows across age groups

, 2011
PurposeTo compare the effects of the tongue-hold swallowing maneuver on pharyngeal pressure generation in healthy young and elderly research volunteers.MethodSixty-eight healthy research volunteers (young, n = 34, mean age = 26.8 years, SD = 5.5; elderly,
Macrae, P., Huckabee, M., Maggie-Lee Huckabee, Doeltgen, S., Sebastian H. Doeltgen, Phoebe Macrae   +5 more
core   +1 more source

Multi-sensor fusion for differentiating swallows between healthy adults and patients with post-stroke dysphagia

Digital Health
Objective The aim of this study was to develop a non-invasive method using multi-sensor fusion to discriminate between abnormal swallows in patients with post-stroke dysphagia and normal swallows in healthy individuals.
Lian Wang, Nannan Cui, Xiaozhen Li, Jia Qiao, Zhenhai Wei, Zulin Dou, Yanxia Liu, Xiaomei Wei   +7 more
doaj   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Using Machine Learning for the Automated Segmentation and Detection of Swallows Obtained by Digital Cervical Auscultation in Preterm Neonates

The clinical application of acoustic swallowing sound parameters collected from digital cervical auscultation is limited because of the time-consuming manual segmentation required by trained experts.
Frakking, Thuy T, Humphries, Seiji, Chang, Anne B, So, Stephen, Frakking, Thuy T., Tadj, Timothy, Schwerin, Belinda, Chang, Anne B.   +7 more
core   +1 more source

Use of Transfer Learning for the Automated Segmentation and Detection of Swallows via Digital Cervical Auscultation in Children [PDF]

Digital cervical auscultation (CA) has high diagnostic test accuracy in the detection of aspiration in children. However, the clinical application of digital CA is limited because swallow sound recordings require manual segmentation by trained experts ...
Frakking, Thuy, So, Stephen, Chang, Anne, Frakking, Thuy T., Tadj, Timothy, Schwerin, Belinda, Chang, Anne B.   +6 more
core   +1 more source

A Pilot Study on Bioaccumulation and Tissue Distribution of Mercury in Barn Swallow (Hirundo rustica)

Toxics
Although extensive research has been carried out on the occurrence of mercury (Hg) in biota, bioaccumulation and tissue distribution of Hg in songbirds have not been well characterized.
Li Tian, Yujing Zhu, Ruiming Yu, Xiaobo Zheng   +3 more
doaj   +1 more source

Bending‐Stable Pressure Sensor Based on Natural Wood Nanofibers for Ultra‐Low Detection Limit

Advanced Science, EarlyView.
A wood nanofiber‐based flexible pressure sensor with intrinsic bending‐stable performance is developed through a porous electrospun architecture and interdigital electrode design. The device exhibits an ultra‐low detection limit and stable operation under deformation for physiological monitoring and spatial sensing, providing a sustainable strategy for
Xu Zeng, Zhengnan Sun, Yilin Wang, Yao Tan, Ranran Xu, Beomjoon Kim, Juergen Brugger, Xiaosheng Zhang   +7 more
wiley   +1 more source

Longitudinal Study of Tree Swallows [PDF]

, 2012
Tree swallows (Tachycineta bicolor) are the most widely distributed of the Tachycineta species, extending from northern Alaska and Canada to the southern United States.
Vleck, Carol, Jaycox, Allison, Vleck, David   +2 more
core