Results 81 to 90 of about 303,787 (348)

Short Wavelength Automated Perimetry and Peripapillary Retinal Nerve Fiber Layer in Early Diabetes

open access: yesPhilippine Journal of Ophthalmology, 2016
Objective: To investigate the significance of short wavelength automated perimetry (SWAP) in detecting retinal functional impairment in early diabetic patients without retinopathy and with mild non-proliferative diabetic retinopathy (NPDR).
Nikki Doreen S. Angbue Te, MD   +4 more
doaj  

Bypassing sluggishness: SWAP algorithm and glassiness in high dimensions

open access: yes, 2018
The recent implementation of a swap Monte Carlo algorithm (SWAP) for polydisperse mixtures fully bypasses computational sluggishness and closes the gap between experimental and simulation timescales in physical dimensions $d=2$ and $3$. Here, we consider
Berthier, Ludovic   +2 more
core   +3 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Interest Rate Swap Market Complexity and Its Risk Management Implications

open access: yesComplexity, 2018
The primary objective of this paper is to study the post Dodd-Frank network structure of the interest rate swap market and propose a set of effective complexity measures to understand how the swap users respond to market risks.
Steve Y. Yang, Esen Onur
doaj   +1 more source

Fast Non-Adiabatic Two Qubit Gates for the Kane Quantum Computer

open access: yes, 2003
In this paper we apply the canonical decomposition of two qubit unitaries to find pulse schemes to control the proposed Kane quantum computer. We explicitly find pulse sequences for the CNOT, swap, square root of swap and controlled Z rotations.
A. Honig   +29 more
core   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Variance Risk Premia [PDF]

open access: yes
We propose a direct and robust method for quantifying the variance risk premium on financial assets. We theoretically and numerically show that the risk-neutral expected value of the return variance, also known as the variance swap rate, is well ...
Liuren Wu, Peter Carr
core  

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