Results 191 to 200 of about 7,174,007 (240)

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

open access: yesiMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang   +10 more
wiley   +1 more source

Hippo in smooth muscle - a therapeutic target in vascular diseases driven by aging and hypertension. [PDF]

open access: yesFront Physiol
Albinsson S   +6 more
europepmc   +1 more source

Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows

open access: yesiMetaOmics, EarlyView.
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang   +7 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

Farmers' Soil–Water Management Practices and Perspectives on Soil Salinization in Mirab Abaya District, Gamo Zone, Southern Ethiopia

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT Soil salinization is a critical threat, impacting 20% of the world's irrigated lands and jeopardizing food security. In Ethiopia's Mirab Abaya district of the Gamo Zone, unsustainable irrigation methods exacerbate this issue. This paper examines local farmers' soil–water management systems and their awareness of salinization, aiming to educate
Oloba Jobe   +3 more
wiley   +1 more source

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