Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang +10 more
wiley +1 more source
Hippo in smooth muscle - a therapeutic target in vascular diseases driven by aging and hypertension. [PDF]
Albinsson S +6 more
europepmc +1 more source
Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang +7 more
wiley +1 more source
Laser powder bed fusion of NiTi: effect of laser power and scanning speed on phase transformation temperatures. [PDF]
Cebrián Carcavilla A, Zaki W.
europepmc +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Grazed bite item diversity of beef cows grazing semi-natural grassland in relation to herbage nutritive value and the actually available diversity of bite items. [PDF]
Siede C +5 more
europepmc +1 more source
Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
wiley +1 more source
Appraisal of Clinical Explanatory Variables in Subtyping of Type 2 Diabetes Using Machine Learning Models. [PDF]
Khamis AH +6 more
europepmc +1 more source
ABSTRACT Soil salinization is a critical threat, impacting 20% of the world's irrigated lands and jeopardizing food security. In Ethiopia's Mirab Abaya district of the Gamo Zone, unsustainable irrigation methods exacerbate this issue. This paper examines local farmers' soil–water management systems and their awareness of salinization, aiming to educate
Oloba Jobe +3 more
wiley +1 more source

