Results 61 to 70 of about 9,392 (185)
Background & objectives: The most common and potentially fatal single-gene hereditary disorder affecting the manufacture of hemoglobin is thalassemia, which results from one or more globin chains fail to synthesize properly, either completely or ...
Sumaia Saif +4 more
doaj +2 more sources
Clinical Impact of Kangaroo Mother Care Implementation on Neonatal Outcomes in District Swat
Background: This study examines the healthcare outcomes, including admissions, improved discharges, deaths, and follow-up visits, for boys and girls in a pediatric healthcare setting from January 2021 to December 2023.
Salman Mastaan Khan +5 more
doaj +1 more source
Amaranth hydrolysate combined with Agastache rugosa extract (AKE) attenuated cancer cachexia in CT26 tumor‐bearing mice by suppressing systemic inflammation and modulating muscle and adipose tissue metabolism. AKE inhibited FoxO3a‐mediated proteolysis while restoring PI3K/Akt/mTOR‐dependent protein synthesis in skeletal muscle.
Junhee Lee +6 more
wiley +1 more source
Effects of Climate Change on Ecologically Sensitive Flows in the Goulburn River Basin, Australia
Freshwater ecosystems face growing threats from climate change and river regulation, which alter natural flow regimes and jeopardise ecological integrity. Our study integrates a SWAT model with ecologically sensitive flow metrics to assess how projected changes in streamflow under future climate scenarios may affect river ecosystem function.
Sudeep Banad +4 more
wiley +1 more source
Objective: To determine the satisfactory sampling rate and safety of free hand fine needle aspiration cytology (FNAC) and ultrasound-guided sampling of thyroid gland. Type of study: Comparative cross-sectional study.
Mohammad Hussain +4 more
doaj
Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim +4 more
wiley +1 more source
OBJECTIVES This study aimed to determine the frequency and pattern of root resorption through radiographic evaluation at Saidu College of Dentistry, Swat.
Abdus Saboor +6 more
doaj
RL-BMAC: An RL-Based MAC Protocol for Performance Optimization in Wireless Sensor Networks
Applications of wireless sensor networks have significantly increased in the modern era. These networks operate on a limited power supply in the form of batteries, which are normally difficult to replace on a frequent basis.
Owais Khan +3 more
doaj +1 more source
EHNN: enhanced hybrid neural network for CRISPR-Cas9 gRNA off-target prediction [PDF]
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated protein 9 (CRISPR-Cas9) is a revolutionary genome editing technology, but its practical utility is limited by off-target effects-unintended DNA cleavage at sites resembling the
Akhtar Sayed +4 more
doaj +2 more sources
Imeglimin Attenuates Skeletal Muscle Atrophy in Mouse Models of Obesity and Ageing
ABSTRACT Background Sarcopenia is a major contributor to frailty and mortality in ageing and obesity and is tightly linked to metabolic dysfunction. Imeglimin is a first‐in‐class oral hypoglycaemic agent targeting mitochondrial function; however, despite the central role of mitochondria in skeletal muscle homeostasis, its effects on skeletal muscle ...
Yangli Ye +7 more
wiley +1 more source

