Results 61 to 70 of about 9,845 (200)

Adipocyte‐Derived KIF13B Aggravates Obesity‐Associated Metabolic Dysfunction via LRP1/PPARγ Signaling

MedComm, Volume 7, Issue 10, October 2026.
Adipocyte‐derived KIF13B promotes LRP1 localization and nuclear LRP1–PPARγ transcriptional activity, thereby enhancing adipogenic gene expression, lipid accumulation, and obesity‐associated metabolic dysfunction. Adipocyte‐specific Kif13b deletion disrupts this LRP1/PPARγ axis, suppresses adipogenic programming, reduces adipose expansion, and protects ...
Guolin Miao, Zhaoling Li, Lianxin Zhang, Yitong Xu, Ziwei Wang, Zixun Wang, Aiden Xian, Liwen Zheng, Jingxuan Chen, Yufei Han, Chunhua Shan, Kaikai Lu, Ming Tao, Ling Zhang, Weiguang Zhang, Wei Huang, Yuhui Wang, Rui Wei, Erdan Dong, Xunde Xian   +19 more
wiley   +1 more source

Impact of the Addition of a Shading Algorithm in a Physically Based Conceptual River Hydrological–Temperature Model

River Research and Applications, Volume 42, Issue 8, Page 1771-1780, October 2026.
ABSTRACT Anthropogenic impacts on the thermal regime of rivers include climate change and deforestation. For the latter, developing modelling tools that can account for the impact of varying vegetation cover on river temperatures is essential. This study describes a new addition to the CEQUEAU hydrological and water temperature model: a shading ...
Zouhir Dichane, Habiba Ferchihi, Cyrille Gatien Kafack Zamo, Jesús Roberto Araujo Sánchez, André St‐Hilaire   +4 more
wiley   +1 more source

From Prediction to Prevention: An Explainable GeoAI Framework for Flood Susceptibility and Urban Exposure Assessment Using Machine and Deep Learning Models

Sustainable Development, Volume 34, Issue 6, Page 8559-8578, October 2026.
ABSTRACT Rapid urbanisation and intensifying rainfall have increased cities' vulnerability to flooding, posing major challenges to sustainable development. Although machine learning models have improved flood prediction accuracy, most remain limited by their black‐box nature and lack of actionable insights.
Abdulwaheed Tella, Izni Zahidi, Chow Ming Fai, Chukwuma Okolie, Quoc Bao Pham   +4 more
wiley   +1 more source

Frequency and Pattern of Root Resorption on Radiographic Inspection Saidu College of Dentistry, Swat - A Cross-Sectional Study.

Journal of Gandhara Medical and Dental Sciences
OBJECTIVES This study aimed to determine the frequency and pattern of root resorption through radiographic evaluation at Saidu College of Dentistry, Swat.
Abdus Saboor, Muhammad Kamran, Ilyas Rahman, Asif Shah, Badshah Afsar, Abdul Wali Khan, Shaffaq Durrani   +6 more
doaj  

Structure–Function Coherent Coarsening for Cross‐Resolution Ecohydrological Modeling

Water Resources Research, Volume 62, Issue 10, October 2026.
Abstract Ecohydrological models are increasingly applied in regional scenario‐based studies, yet their cross‐resolution application remains constrained by high computational costs of fine‐resolution simulations and by structural inconsistencies introduced during scale transfer.
Long Jiang, Yang Yang, Morgan Thornwell, Robert McKane, Sonali Chokshi, Huanfeng Duan, Tiantian Yang, Hoshin Vijai Gupta   +7 more
wiley   +1 more source

Outcome of Open Reduction and Internal Fixation by Using One Titanium Plate and Archbar for the Management of Mandibular Fractures in Symphyseal and Parasymphyseal Region

Journal of Gandhara Medical and Dental Sciences
OBJECTIVES To determine nerve injury, malocclusion, and non-union of ORIF using a single miniplate and arch bar in the treatment of mandibular fractures in the parasymphyseal and symphyseal regions.
Abdul Wali Khan , Khadija Syed , Salman Khan, Azmat Ali Safwan, Abdus Saboor, Ajmal Khan, Majida Rahim   +6 more
doaj  

RL-BMAC: An RL-Based MAC Protocol for Performance Optimization in Wireless Sensor Networks

Information
Applications of wireless sensor networks have significantly increased in the modern era. These networks operate on a limited power supply in the form of batteries, which are normally difficult to replace on a frequent basis.
Owais Khan, Sana Ullah, Muzammil Khan, Han-Chieh Chao   +3 more
doaj   +1 more source

EHNN: enhanced hybrid neural network for CRISPR-Cas9 gRNA off-target prediction [PDF]

PeerJ Computer Science
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated protein 9 (CRISPR-Cas9) is a revolutionary genome editing technology, but its practical utility is limited by off-target effects-unintended DNA cleavage at sites resembling the
Akhtar Sayed, Kifayat Ullah, Muzammil Khan, Rayed Alakhtar, Huda Alsobhi   +4 more
doaj   +2 more sources

Assessing Hydrological Model Representation of Irrigation and Subsurface Flow in a Heavily Anthropogenic‐Influenced Catchment

Water Resources Research, Volume 62, Issue 10, October 2026.
Abstract Evaluating water availability in catchments with widespread anthropogenic influences demands a joint analysis of natural hydrological processes and anthropogenic influences. Achieving this through hydrological modeling requires proper representation of relevant processes. Beyond the application of a single model set‐up, we assess the impact of
Raul Mendoza, Willem van Verseveld, Frederiek Sperna Weiland, Anjali Bhagwat, Chris Seijger, Albrecht Weerts   +5 more
wiley   +1 more source

Dynamic Land Use Change in SWAT+: A Novel Application of Scenario Decision Tables

JAWRA Journal of the American Water Resources Association, Volume 62, Issue 5, October 2026.
ABSTRACT Land use and land cover (LULC) changes significantly impact hydrological processes, yet their dynamic representation in hydrological models remains a challenge. This paper introduces and pioneers the use of the newly implemented capability of SWAT+ to simulate dynamic LULC changes using “land use scenario decision tables”.
Lucas Alcamo, Jeff Arnold, Timo Schaffhauser, Natalja Cerkasova, Markus Disse   +4 more
wiley   +1 more source