Results 291 to 300 of about 389,091 (415)

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

Wearable MXene-enhanced organic Bio-FET paper patch for glucose detection in sweat with pH and temperature calibration. [PDF]

Sci Rep
Farahmandpour M, Kordrostami Z.
europepmc   +1 more source

Effect of Adrenalectomy on the Excitability of Plantar Sweat Glands in Albino Rats

, 1959
Kazukuni Yamashita
openalex   +2 more sources

Unveiling the Excited‐State Dynamics and Interfacial Interactions in Dye‐Sensitized NaNdF4 Nanoparticles for Efficient Photothermal Effect

Advanced Science, EarlyView.
A new class of efficient photothermal agents based on dye‐sensitized NaNdF4 is developed. The coordination and aggregation states of cypate dyes on lanthanide nanoparticles are identified, revealing the influence of interfacial interactions on resonant energy transfer and synergetic heat generation.
Jiacheng Gong, Wusen Zhou, Zhuo Li, Xingjun Li, Wen Yuan, Xiaobo Gu, Qianqian Niu, Yan Liu, Jin Xu, Renfu Li, Datao Tu, Shan Lu, Xueyuan Chen   +12 more
wiley   +1 more source

Case Reflection of a Child With p.Phe312del/p.Phe508del Genotype Undetected on Newborn Screening and With No Clinical Features of Cystic Fibrosis Despite a Sweat Chloride Value in the Diagnostic Range. [PDF]

Cureus
Clarke J, Gadelsayed N, Elsammak M, Brady J, Elnazir B.   +4 more
europepmc   +1 more source

Cancer Specific CAIX‐Targeting Supramolecular Lysosome‐Targeting Chimeras (Supra‐LYTAC) for Targeted Protein Degradation

Advanced Science, EarlyView.
Spatiotemporal Supra‐LYTAC formation near cancerous membrane via CAIX‐targeting is achieved. As a result of generation of Supra‐LYTAC, POI trafficking into lysosome is significantly implemented for targeted protein degradation. Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable ...
Dohyun Kim, Gyeongseok Yang, Chaelyeong Lim, Gaeun Park, Jaemo Lee, Youjung Sim, Ja‐Hyoung Ryu   +6 more
wiley   +1 more source

The Acari Hypothesis, VII: accounting for the comorbidity of allergy with other contemporary medical conditions, especially metabolic syndrome. [PDF]

Front Allergy
Retzinger AC, Retzinger GS.
europepmc   +1 more source

Bioinspired Liquid‐Free Ion‐Conductive Elastomers with Ultrahigh Mechanical Strength and Excellent Ionic Conductivity for Multifunctional Flexible Sensing Applications

Advanced Science, EarlyView.
⁻Inspired by the “brick wall” structure of pearl layer, FLICE‐110% liquid‐free ionic conductive elastomer had high mechanical strength (5.46 MPa), excellent ionic conductivity (3.29 × 10−4 S cm−1) and resilience. It can be used in smart music boxes, airplane wings and control manipulators.
Zequan Li, Jingjing Tang, Xuwei Wang, Fuqi Wang, Fangyan Ou, Wenyu Pan, Changsheng Wang, Ting Xie, Chuang Ning, Xiwei Xu, Jiamin Liu, Qihua Liang, Wei Gao, Shuangliang Zhao   +13 more
wiley   +1 more source

A programmable magnetic digital microfluidic platform integrated with electrochemical detection system. [PDF]

Microsyst Nanoeng
Zhao Y, Jiang S, Cai G, Wang L, Zhao J, Feng S.   +5 more
europepmc   +1 more source

Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non‐Canonical Amino Acids for Coinhibition of MCL‐1 and BCL‐xL in Acute Myeloid Leukemia

Advanced Science, EarlyView.
A structure‐guided peptide derived from a non‐canonical amino acid library simultaneously targets MCL‐1 and BCL‐xL to overcome apoptotic resistance in acute myeloid leukemia. Fused with a CXCR4‐binding motif, the engineered peptide exhibits selective intracellular delivery and potent in vivo efficacy, offering a promising therapeutic strategy against ...
Zhe Wang, Ruizhi Lai, Xinpei Wang, Xu Chen, Youjian Zhou, Shengbin Li, Xiaohui Qiu, Zekai Zeng, Jianye Yuan, Jinghuan Mao, Zhidong Chen, Junqing Wang   +11 more
wiley   +1 more source