Results 41 to 50 of about 91,840 (318)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Wilson protein expression, copper excretion and sweat production in sweat glands of Wilson disease patients and controls

open access: yesBMC Gastroenterology, 2008
Background In Wilson disease, copper is not sufficiently excreted into bile due to the absence or malfunction of the Wilson protein copper ATPase in the excretory pathway of hepatocytes. Copper is found in sweat. It is unknown if the Wilson protein plays
Weiss Karl   +4 more
doaj   +1 more source

Excitement-Induced Cutaneous Bleeding (Haematidrosis-like) in a Dog

open access: yesVeterinary Sciences, 2021
A 15-month-old intact female Pitbull was referred because of recurrent, episodic, self-limiting, excitement-induced bleeding from nontraumatised skin. No abnormalities were detected upon physical examination.
Evi I. Sofou   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Metabolomics Approach for Sweat Mapping the Performance of Soccer Players in Pretoria, South Africa

open access: yesApplied Sciences
Exercise is one of the main challenges to the body’s homeostasis since it needs an immediate, substantial rise in ATP re-synthesis, which leads to the prevention of response capacity and performance of players.
Nong Malefo   +4 more
doaj   +1 more source

Sweat sodium is not sweat chloride [PDF]

open access: yesArchives of Disease in Childhood, 1997
Editor,—We read the annotation on the diagnosis of cystic fibrosis with great interest.1 However, some points about the sweat test that were made are potentially misleading and unfairly denigrate a valuable diagnostic tool. We were interested in the statement that ‘10% of normal adolescents will have sweat salt concentrations greater than 60 mmol/l ...
S K HALL, S M KEFFLER, P WELLER, A GREEN
openaire   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin

open access: yesmSphere, 2020
Emerging pathogen Candida auris causes nosocomial outbreaks of life-threatening invasive candidiasis. It is unclear how this species colonizes skin and spreads in health care facilities. Here, we analyzed C.
Mark V. Horton   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Latherin: a surfactant protein of horse sweat and saliva [PDF]

open access: yes, 2009
Horses are unusual in producing protein-rich sweat for thermoregulation, a major component of which is latherin, a highly surface-active, non-glycosylated protein.
Douglas L Bovell   +33 more
core   +1 more source

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