Results 171 to 180 of about 208,077 (237)

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Trisulfated Heparin Disaccharide (TS-HDS) Antibody-Positive Small Fiber Neuropathy Involving Sweat Gland Nerve Fibers After the Second Moderna Vaccination: A Case Report. [PDF]

Cureus
Finsterer J.
europepmc   +1 more source

Small molecules facilitate single factor-mediated sweat gland cell reprogramming. [PDF]

Mil Med Res, 2022
Ji SF, Zhou LX, Sun ZF, Xiang JB, Cui SY, Li Y, Chen HT, Liu YQ, Gao HH, Fu XB, Sun XY.   +10 more
europepmc   +1 more source

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Endocrine mucin-producing sweat gland carcinoma of eyelid as a presenting feature of breast carcinoma in a male patient. [PDF]

Oman J Ophthalmol
Sehgal T, Verma R, Singh A, Gupta Y.
europepmc   +1 more source

Foxa1 mediates eccrine sweat gland development through transcriptional regulation of Na-K-ATPase expression. [PDF]

Braz J Med Biol Res, 2022
Zhao J, Zhang L, Du L, Chen Z, Tang Y, Chen L, Liu X, You L, Zhang Y, Fu X, Li H.   +10 more
europepmc   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar, Egor B. Skryabin, Bettina M. Buchholz, Michaela Kuhn, Celso E. Gomez‐Sanchez, Stepan Gambaryan, Viacheslav O. Nikolaev   +6 more
wiley   +1 more source

Role of Adjuvant Radiotherapy in Sweat Gland Carcinoma: A Case Report and Literature Review. [PDF]

Cureus
Bhattacharjee A, Lahiri D, Ghosh R, Chakraborty D.   +3 more
europepmc   +1 more source

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

British Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan, Rwdah Mohamed Alameri, Yasir S. Raouf, Damien Maurel, Naiem Ahmad Wani, Anatoliy Shmygol, Irfa Anwar, Heng B. See, Elizabeth K. M. Johnstone, Elodie Dupuis, Eric Trinquet, Kevin D. G. Pfleger, Emilia Oueis, Mohammed Akli Ayoub   +13 more
wiley   +1 more source

Endocrine Mucin-Producing Sweat Gland Carcinoma (EMPSGC) in a Dog: Immunohistochemical Characterization. [PDF]

Animals (Basel)
Tangchang W, Jung GY, Song JY, Kumbukgahadeniya P, Kim DH, Kwon HJ, Son HY.   +6 more
europepmc   +1 more source