Results 241 to 250 of about 37,419 (303)

Heat stress alters metabolic pathways and nitric oxide signaling in keratinocytes under hyperglycemia

Journal of Diabetes Investigation, EarlyView.
This illustration depicts the effects of thermal stress on human keratinocytes maintained in both normal and high‐glucose conditions. Under normal glucose conditions, heat exposure enhances arginine metabolism and increases nitric oxide (NO) production, which promotes alterations in mitochondrial morphology and elevates heat shock protein 70 (Hsp70 ...
Syeda Tayyiba Rahat, Ilkka Miinalainen, Anni I. Nieminen, Seppo Vainio, Nsrein Ali   +4 more
wiley   +1 more source

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

Journal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu, Agata Kurowski, Malini P. Naidu, Jonas Adalsteinsson, Shane A. Meehan, Natalia Alkon, Lauren R. Port, Sumanth Chennareddy, Emry R. Cohenour, Grace Christensen, Jonah Shulman, Nicholas Gulati, Constanze Jonak, Patrick M. Brunner   +13 more
wiley   +1 more source

Global consensus on the management of melanin hyperpigmentation disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron, Seemal R. Desai, Marwa Abdallah, Firas Al‐Niaimi, Ncoza Dlova, Pearl E. Grimes, Jorge Ocampo‐Candiani, Rashmi Sarkar, Leihong Flora Xiang, Helio Amante Miot   +9 more
wiley   +1 more source

Second Asian Consensus Report on Functional Dyspepsia (2025): Updated Recommendations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Functional dyspepsia (FD) is a common gastrointestinal disorder that significantly impacts patients' quality of life. Over a decade ago, the Asian Neurogastroenterology and Motility Association (ANMA) and the Asian Pacific Association of Gastroenterology (APAGE) jointly developed the first Asian consensus report on FD.
Sanjiv Mahadeva, Kewin Tien Ho Siah, Uday C. Ghoshal, Hidekazu Suzuki, Yeong Yeh Lee, Kee Huat Chuah, Vincent Chung, Linda Zhong, Benjamin Wei‐Rong Tay, Ban Hong Ang, Ram Prasad Sinnanaidu, Tao Bai, Tadayuki Oshima, Tanisa Patcharatrakul, Sanjeev Sachdeva, Ping‐Huei Tseng, Jinsong Liu, Yinglian Xiao, Ratha‐Korn Vilaichone, Joon Seong Lee, Jung‐Hwan Oh, Ari Fahrial Syam, Ching Liang Lu, Tiing Leong Ang, In‐Kyung Sung, Xiao‐Hua Hou, Kentaro Sugano, Justin Wu, Hiroto Miwa   +28 more
wiley   +1 more source

Personal and Environmental Factors Influencing Self‐Determination of People With Intellectual Disabilities and Epilepsy: A Scoping Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Epilepsy is a chronic neurological disorder that is prevalent among people with intellectual disabilities, profoundly affecting various aspects of life. Understanding the association between epilepsy and reduced quality of life in this population may benefit from exploring self‐determination, a key dimension of quality of life. Self‐
Alexandra I. Haenen, Noud Frielink, Jans S. van Ool, Francesca M. Snoeijen‐Schouwenaars, Petri J. C. M. Embregts   +4 more
wiley   +1 more source

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Sweat Gland Carcinoma

The American Surgeon, 2004
Sweat gland carcinoma is a rare malignant tumor of the skin adnexa that can occur in a variety of locations. It is a slow-growing tumor that metastasizes early and often. The rarity of this tumor has led to a relative lack of adequate evidence with regard to treating this entity. Recent advances in immunohistochemical staining have better defined this
Igor, Brichkov, Theodoros, Daskalakis, Linda, Rankin, Celia, Divino   +3 more
openaire   +2 more sources

Eccrine sweat gland disorders

Journal of the American Academy of Dermatology, 1991
I. Classification and diagnostic approaches 1. Following is a tentative classification of eccrine sweat disorders according to the pathogenesis and the size of the involved area. It is intended solely as a guide for evaluation of sweating di .so. rders in patients.
K, Sato, M, Ohtsuyama, G, Samman
openaire   +2 more sources

Polymorphous sweat gland carcinoma

Histopathology, 1994
We describe nine cases of a distinctive cutaneous neoplasm showing features of eccrine adnexal differentiation that were characterized by their variegated histological appearance and low‐grade malignant behaviour. The term polymorphous sweat gland carcinoma is proposed to designate these lesions.
S, Suster, T Y, Wong
openaire   +2 more sources

Metastatic sweat gland carcinoma

The Laryngoscope, 1978
AbstractOnly 48 cases of metastatic sweat gland carcinoma have been published. Our case report is of an elderly lady with a sweat gland carcinoma of the scalp with metastatic disease in the neck. She was treated with radical neck dissection and wide local excision. Follow‐up of three years has revealed no recurrence.
J T, Fierstein, S E, Thawley, N S, Druck, J H, Ogura   +3 more
openaire   +2 more sources