Results 101 to 110 of about 67,555 (264)

Current Insights of the Potential Plant Bioactive Compounds on Modulating the mTOR Signaling Pathway in Regulating Oncological Disorders

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Deregulation of the mechanistic target of the rapamycin (mTOR) pathway plays an important role in cancer genesis and progression, making it an attractive target for cancer treatment. Disrupting the mTOR pathway contributes to uncontrolled cell growth, increased proliferation, and enhanced cell survival, all of which are hallmarks of cancer ...
Sonali Khanal   +9 more
wiley   +1 more source

Cystic Fibrosis Transport Regulator and its mRNA are Expressed in Human Epidermis [PDF]

open access: yes, 2002
Cystic fibrosis transport regulator is a cAMP-dependent chloride channel protein. Normal (non cystic fibrosis) human epidermis stained positive for cystic fibrosis transport regulator as densely as did the eccrine sweat gland when three monoclonal ...
Sato, Fusako   +3 more
core   +10 more sources

Apocrine carcinoma of the scalp with neck lymph node metastasis: A case report and review of the literature

open access: yesJournal of Family Medicine and Primary Care, 2019
Primary cutaneous apocrine carcinoma (PCAC) is an extremely rare malignancy. Distinguishing apocrine carcinoma from breast carcinoma metastasis is difficult. Only a few cases reported as PCAC of the scalp and primarily treated by wide local excision. The
Hadi Al-Hakami   +4 more
doaj   +1 more source

Single‐Cell Transcription Reveals the Fibroblast Heterogeneity and Neural Cells' Significance in Desmoid Fibromatosis

open access: yesCancer Science, EarlyView.
Mesenchymal fibroblasts were significantly expanded in desmoid fibromatosis (DF), and the mesenchymal fibroblasts in DF were further divided into two subtypes according to the differentiation states. ADAM12 and CREB3L1 were identified as the specific marker and transcription factor for DF.
Junfeng Wang   +7 more
wiley   +1 more source

An Unusual Case of Squamoid Eccrine Carcinoma of the Abdominal Wall with Inguinal Nodal Metastases: A Case Report and Review of the Literature [PDF]

open access: yesIranian Journal of Colorectal Research, 2019
Introduction: Squamoid eccrine carcinoma is a very rare carcinoma with few reported cases in the literature. As a result, there islimited guidance on management and follow-up of these cases.Case Presentation: We describe the case of a 39 year-old male ...
Brenna L. Hennessey   +8 more
doaj  

Wide excision and reconstruction surgery for recurrent sweat gland umbilical adenocarcinoma followed by chemotherapy can prevent the risk of recurrences

open access: yesBMC Surgery, 2018
Background Adenocarcinoma derived from umbilicus is very rare. Most adenocarcinomas in umbilicus are secondary events. Carcinoma derived from sweat glands is sporadic, highly radioresistant and has a clinical appearance that is difficult to predict. Case
Adeodatus Yuda Handaya   +3 more
doaj   +1 more source

Clinical presentation and treatment of multifocal epitrichial sweat gland carcinoma in a horse

open access: yesAustral journal of veterinary sciences, 2020
. Epitrichial gland carcinoma is a very rare type of skin tumour in horses. This report describes a horse presenting multiple nodules with associated normal, alopecic and ulcerated skin diagnosed via histopathology as epitrichial gland carcinoma ...
Cristóbal A. Dörner   +2 more
semanticscholar   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Endocrine Mucin-Producing Sweat Gland Carcinoma in an Elderly Man.

open access: yesAmerican journal of dermatopathology, 2020
complementary explanation may lie in the identification of label-retaining cells with myoepithelial features and stem cell behavior, localized in the basal layer of the secretory acinar region of sweat glands, lying at the border of the dermis and ...
Sheevam Shah, P. Parekh, M. Rodriguez
semanticscholar   +1 more source

Chondroid Syringoma and Eccrine Spiradenoma [PDF]

open access: yes, 2011
Fine needle aspiration cytology (FNAC) is a well established diagnostic tool. However, most clinicians prefer to diagnose suspected skin tumors by excisional biopsy as they are easily accessible and hence benign skin adnexal tumors are rarely encountered
Fernandes, H   +6 more
core  

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