Results 11 to 20 of about 9,209 (235)

The possibility of using skin biopsy in the diagnosis of Lafora disease

Бюллетень сибирской медицины, 2020
Lafora disease is a hereditary, autosomal recessive progressive myoclonus epilepsy caused by mutations in the EPM2A (laforin) and EPM2B (malin) genes, with no substantial genotype-phenotype differences between the two.
L. S. Kraeva, S. V. Vtorushin, A. V. Kuzmina, D. V. Kozyritskaya   +3 more
doaj   +1 more source

Defining Key Genes Regulating Morphogenesis of Apocrine Sweat Gland in Sheepskin

Frontiers in Genetics, 2019
The apocrine sweat gland is a unique skin appendage in humans compared to mouse and chicken models. The absence of apocrine sweat glands in chicken and murine skin largely restrains further understanding of the complexity of human skin biology and skin ...
Shaomei Li, Xinting Zheng, Yangfan Nie, Wenshuo Chen, Zhiwei Liu, Yingfeng Tao, Xuewen Hu, Yong Hu, Haisheng Qiao, Quanqing Qi, Quanbang Pei, Danzhuoma Cai, Mei Yu, Chunyan Mou   +13 more
doaj   +1 more source

Prevalence of skin diseases of the pediatric population in the Southeastern Anatolia, Turkey

Medicine Science, 2018
Skin diseases are quite common in childhood and affected by geographic, cultural, and socio-economic conditions. There is no reported study about the prevalence of skin diseases of the pediatric population in the Southeastern Anatolia, Turkey.
Asude Kara Polat, Yavuz Yesilova, Emine Tugba Alatas, Asli Akin Belli, Gursoy Dogan, Metin Picakciefe   +5 more
doaj   +1 more source

Sweat in Skin Homeostasis and Dermatological Disorders in Athletes: Structural, Functional, and Clinical Perspectives - A Narrative Review

Journal of Education, Health and Sport
Introduction and purpose. Sweat is essential for skin homeostasis. In physically active individuals, increased sweating supports protective skin functions but may also trigger dermatological conditions.
Monika Jarowicz, Zuzanna Marczak, Maksymilian Sito, Filip Jurkowski, Łukasz Wójcik, Natalia Gawron, Hubert Tomasz Bojanowski, Aleksandra Dobracka, Kinga Zachar, Jędrzej Czmyr   +9 more
doaj   +1 more source

Wilson protein expression, copper excretion and sweat production in sweat glands of Wilson disease patients and controls [PDF]

BMC Gastroenterology, 2008
In Wilson disease, copper is not sufficiently excreted into bile due to the absence or malfunction of the Wilson protein copper ATPase in the excretory pathway of hepatocytes. Copper is found in sweat. It is unknown if the Wilson protein plays a role in copper excretion into sweat. It is the aim of this study to investigate Wilson protein expression in
Weiss Karl, Merle Uta, Schellenberg Mavi, Schaefer Mark, Stremmel Wolfgang   +4 more
openaire   +3 more sources

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

A Review on Bioengineering the Bovine Mammary Gland: The Role of the Extracellular Matrix and Reconstruction Prospects

Bioengineering
The mammary gland is a modified sweat gland responsible for milk production. It is affected by diseases that reduce animals’ quality of life, consequently leading to economic losses in livestock.
Fernando Chissico Júnior, Thamires Santos da Silva, Flávio Vieira Meirelles, Paulo Sérgio Monzani, Lucas Fornari Laurindo, Sandra Maria Barbalho, Maria Angélica Miglino   +6 more
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

Advanced Healthcare Materials, EarlyView.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître, Marina Trouillas, Tatiana Vinasco‐Sandoval, Cécile Giordano, Alexandre G. Lellouch, Walid Rachidi, Jean‐Jacques Lataillade, Nicolas O. Fortunel   +7 more
wiley   +1 more source