Results 71 to 80 of about 9,209 (235)

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Extramammary Paget's disease. Arising in knee region in association with sweat gland carcinoma.

Archives of pathology & laboratory medicine, 1984
We report a case of extramammary Paget's disease (EMPD) arising in the knee region in association with an underlying sweat gland carcinoma. Inguinal lymph node metastases were present initially. Paget's cells, intradermal tumor cells, and metastatic tumor cells showed similar reactions to a variety of histochemical stains and positive results with ...
G G, de Blois, J W, Patterson, S B, Hunter   +2 more
openaire   +1 more source

Wild Pigs (Sus scrofa) Stand Their Ground: Investigating Flight Response, or Lack Thereof, to Perceived Predation Risk 野猪坚守原地:探究其面对感知捕食风险时的逃逸反应 (或无逃逸行为)

Wildlife Letters, EarlyView.
We used automated behavioral response systems (ABRs) to assess invasive wild pig (Sus scrofa) behavioral response to four auditory playbacks: humans, coyote vocalizations (Canis latrans), pigs in distress, and barred owl (Strix varia) calls. Wild pigs had a significant flight response to human playbacks, but 68% of pigs did not flee.
Justine L. Smith, L. Mike Conner, Michael T. Mengak   +2 more
wiley   +1 more source

Segmental Pallor and Hair Loss in a Patient With Ross Syndrome: Case Report

The Journal of Dermatology, EarlyView.
ABSTRACT A 30‐year‐old male sought medical consultation due to sudden anisocoria. Clinical examination confirmed Adie's tonic pupil. Subsequently, the presence of segmental anhidrosis with compensatory hyperhidrosis and areflexia established the diagnosis of Ross syndrome.
Markus Augusto Martínez Holst, Ana María Sierra Valiente, Francisco Alejandro Silva Navarro, Paola Picazo León, Carolina De La Paz Cruz, Frida Aguilera Villa   +5 more
wiley   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Occupational Physical Activity Is Negatively Associated With Semen Quality

Andrology, EarlyView.
ABSTRACT Background Lifestyle factors have been associated with semen quality and have been implicated in the reported global decline in semen parameters. Moderate physical activity has been linked to improved semen quality; however, the association between occupational physical activity and semen quality is limited.
Michal Efrat, Sharon Barak, Anat Stein, Haim Pinkas, Ron Unger, Ruth Birk   +5 more
wiley   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Sweat glands in action: the role of biological and environmental factors, exercise, and dermatologic conditions in sudomotor function. [PDF]

Korean J Physiol Pharmacol
Na S, Lee HJ, Park TH, Kim J, Jung YH, Cha M, Lee HY, Kim HJ, Lee JB.   +8 more
europepmc   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Sweat components as a promising monitoring tool for systemic diseases. [PDF]

J Physiol Sci
Shi C, Chen Z, Zhang L, Zhang X, Liang X, Yan L, Hao X, Dong G, Lu C, Huang L.   +9 more
europepmc   +1 more source