TRPS1 Is Differentially Expressed in a Variety of Malignant and Benign Cutaneous Sweat Gland Neoplasms. [PDF]
Neoplasms of sweat glands and the breast may be morphologically and immunophenotypically similar. A recent study showed that TRPS1 staining is a highly sensitive and specific marker for breast carcinoma. In this study, we analyzed TRPS1 expression in a spectrum of cutaneous sweat gland tumors.
Zengin HB+5 more
europepmc +8 more sources
The role of radiotherapy in the treatment of malignant sweat gland neoplasms [PDF]
Malignant sweat gland neoplasms are rare tumors. Historically, the principal mode of treatment has been local surgical excision. Eight published studies show that greater than 50% of patients develop either local tumor recurrence after surgery or regional lymph node metastases.
Jerry L. Bangert+3 more
semanticscholar +5 more sources
TRPS1 Expression in Non-Melanocytic Cutaneous Neoplasms: An Immunohistochemical Analysis of 200 Cases [PDF]
BACKGROUND: Although trichorhinophalangeal syndrome type 1 (TRPS1) was initially thought to be highly sensitive and specific for carcinomas and mesenchymal tumors of mammary origin, more recent data suggest its expression is not limited to breast ...
Aung, Phyu P+10 more
core +5 more sources
Skin adnexal neoplasms—part 2: An approach to tumours of cutaneous sweat glands [PDF]
Tumours of cutaneous sweat glands are uncommon, with a wide histological spectrum, complex classification and many different terms often used to describe the same tumour. Furthermore, many eccrine/apocrine lesions coexist within hamartomas or within lesions with composite/mixed differentiation.
Danny Ghazarian+2 more
openaire +4 more sources
Mechanistic and Treatment Implications of ΔNp63 Expression in a Rare Case of Metastatic Hidradenocarcinoma [PDF]
Hidradenocarcinomas are rare, aggressive adnexal tumors of sweat gland origin that demonstrate a high potential for local recurrence, metastasis and poor outcome.
Driscoll, James J.+2 more
core +8 more sources
SMAS flap for extracapsular dissection of parotid gland tumors: is it necessary? [PDF]
Objective: The aim of this retrospective article is to evaluate postoperative outcomes after extracapsular dissection for small benign superficial parotid neoplasms (<3 cm) in patients who received Superficial Musculoaponeurotic System (SMAS) flap and
Becelli, Roberto+8 more
core +2 more sources
Eccrine porocarcinoma of the head: An important differential diagnosis in the elderly patient [PDF]
Background: Eccrine porocarcinoma is a rare malignant tumor of the sweat gland, characterized by a broad spectrum of clinicopathologic presentations. Surprisingly, unlike its benign counterpart eccrine poroma, eccrine porocarcinoma is seldom found in ...
Akiyoshi E+25 more
core +1 more source
Exploring the interdependencies of research funders in the UK [PDF]
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P+13 more
core +1 more source
Eyelid microcystic adnexal carcinoma [PDF]
Microcystic adnexal carcinoma is an uncommon cutaneous tumor with multiple synonyms. On cursory microscopic examination, the tumor mimics syringoma and other benign skin adnexal tumors.
Griener, Eric+3 more
core +1 more source
Hidradenocarcinoma of the Female Breast: A Surgical Approach to a Rare Skin Tumor [PDF]
Clear-cell hidradenocarcinomas are extremely uncommon sweat gland tumors with a predilection for the head and neck. In the limited number of articles reporting breast involvement, the primary focus concerns this entity's histological and ...
Abreu de Sousa, Joaquim+4 more
core +1 more source