Results 131 to 140 of about 4,315 (262)
Seamless, modular binary vectors for plant cell and molecular biology
Summary In plants, genetic manipulations are commonly performed using Agrobacterium tumefaciens, a plant pathogen whose abilities as a ‘natural genetic engineer’ have been co‐opted for biotechnological applications. In the widely used binary vector systems, Agrobacterium already contains a plasmid with most of the genes needed for virulence and is ...
Rory Greenhalgh+5 more
wiley +1 more source
Women in space: A review of known physiological adaptations and health perspectives
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford+4 more
wiley +1 more source
The therapeutic role of exercise training during menopause for reducing vascular disease
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing+4 more
wiley +1 more source
Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins
Abstract figure legend Figure depicts the key finding from this study. While loss of all dynamins severely debilitates synaptic vesicle retrieval following repetitive activity, retrieval and recycling of individual synaptic vesicles following spontaneous fusion or sparse stimulation are minimally affected.
Olusoji A. T. Afuwape+4 more
wiley +1 more source
Comprehensive management of vulvovaginal cancers
Abstract Vulvar and vaginal cancers represent rare malignancies, with an incidence of 2.7 per 100,000 women for vulvar cancer, predominantly affecting women older than 60 years, although rising rates are observed in younger demographics. Approximately 90% of vulvar cancers are squamous cell carcinoma and frequently are associated with human ...
Angélica Nogueira‐Rodrigues+5 more
wiley +1 more source
CDK4/6 inhibitor in combination with aromatase inhibitor effective in metastatic hidradenocarcinoma
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Valerie Glatzel+6 more
wiley +1 more source
Recent Progress in Gene Delivery Systems Based on Gemini‐Surfactant
Gene delivery is a key area in biomedicine, where nucleic acids are delivered into cells to treat diseases by modulating genes. The low micelle concentration, effective nucleic acid complexation, and low immunogenicity make Gemini surfactants promising gene delivery vectors.
Peng Qian+5 more
wiley +1 more source
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi+5 more
wiley +1 more source
Nanoparticles are transforming animal care by enhancing nutrition, drug delivery and disease prevention. This study highlights their role in improving nutrient absorption in livestock, facilitating targeted drug delivery and boosting vaccine efficacy. Additionally, nanoparticles effectively reduce harmful mycotoxins in animal feeds, promoting overall ...
Mohsen Kazemi
wiley +1 more source