Results 141 to 150 of about 34,170 (296)

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

New Anti‐Fibrotic Strategies for Keloids: Insights From Single‐Cell Multi‐Omics

open access: yesCell Proliferation, EarlyView.
Our research not only revealed the ubiquity and activity of POSTN‐positive mesenchymal fibroblasts in keloids but also discovered the predominant role of IGFBP2‐positive fibroblasts in normal skin and their potential significance in the process of anti‐fibrotic therapy.
Songyun Zhao   +16 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Physical, but not laboratory, treatment‐related adverse events are associated with favorable outcomes of enfortumab vedotin for advanced urothelial carcinoma: A landmark analysis

open access: yesInternational Journal of Urology, Volume 32, Issue 3, Page 270-276, March 2025.
Abstract Background While the occurrence of immune‐related adverse events has been recognized as a prognostic marker in patients receiving immune checkpoint inhibitors, the prognostic significance of treatment‐related adverse events (trAEs) in patients undergoing antibody–drug conjugates such as enfortumab vedotin (EV) is controversial.
Satoru Taguchi   +37 more
wiley   +1 more source

A Predictive Model of Pressure Injury in Children Undergoing Living Donor Liver Transplantation Based on Machine Learning Algorithm

open access: yesJournal of Advanced Nursing, Volume 81, Issue 6, Page 3003-3012, June 2025.
ABSTRACT Aims The aim of our study was to formulate and validate a prediction model using machine learning algorithms to forecast the risk of pressure injuries (PIs) in children undergoing living donor liver transplantation (LDLT). Design A retrospective cohort study.
Xiaomei Chen   +6 more
wiley   +1 more source

Topographical variations in the skin barrier and their role in disease pathogenesis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Unlike the gut, the skin appears uniform at first glance. However, histological and molecular biological research has revealed significant regional variations in the composition and function of its main barrier elements. In this review, we describe the topographical differences of four barrier elements in healthy skin: microbiome, chemical, physical ...
Z. Dajnoki   +5 more
wiley   +1 more source

‘Case of the Month’ from the University of Verona, Italy—navigating the medical and surgical challenges of urinary bladder paraganglioma: insights from a clinical case

open access: yes
BJU International, Volume 135, Issue 5, Page 743-747, May 2025.
Lorenzo Pierangelo Treccani   +8 more
wiley   +1 more source

Hodgkin Lymphoma of the Parotid Gland: An Unusual Presentation in a Paediatric Patient

open access: yesOral Surgery, EarlyView.
ABSTRACT Background Malignancy involving the salivary glands is a rare occurrence; of these malignancies occurring in the salivary glands, the majority are associated with the parotid glands. Lymphoma is a rare occurrence in the parotid glands and salivary glands in general, and the majority of these are non‐Hodgkin lymphoma (NHL). Hodgkin lymphoma (HL)
Daniel Dilworth   +3 more
wiley   +1 more source

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