Results 161 to 170 of about 4,315 (262)

Crizotinib: A Novel Strategy to Reverse Immunosuppression in Melanoma by Targeting Lactate Transport

MedComm, Volume 6, Issue 8, August 2025.
Crizotinib inhibits CD147‐MCT1‐mediated lactate transport, suppressing melanoma growth and immune escape, prevents M2 macrophage polarization, and enhances immunotherapy by reducing CXCL13 via histone lactylation. ABSTRACT Lactate is a vital metabolite in cancer, significantly impacting tumor progression, metastasis, and overall survival.
Zhe Zhou, Xu Zhang, Susi Zhu, Waner Liu, Yeye Guo, Siyu Xiong, Cong Peng, Xiang Chen   +7 more
wiley   +1 more source

Digital Papillary Adenocarcinoma Is HPV-42-Associated and BRAFV600E Negative: Perspectives for Diagnostic Practice. [PDF]

Dermatopathology (Basel)
Dege T, Rütten A, Goebeler M, Kneitz H.
europepmc   +1 more source

Sézary Syndrome—Eosinophilia Explained by a Blood Film

American Journal of Hematology, Volume 100, Issue 8, Page 1423-1424, August 2025.
Merel T. A. Soeterik, Joris Janssen, Leo M. Budel, Anton W. Langerak, Yorick Sandberg, Barbara J. Bain   +5 more
wiley   +1 more source

Hodgkin Lymphoma of the Parotid Gland: An Unusual Presentation in a Paediatric Patient

Oral Surgery, Volume 18, Issue 3, Page 348-353, August 2025.
ABSTRACT Background Malignancy involving the salivary glands is a rare occurrence; of these malignancies occurring in the salivary glands, the majority are associated with the parotid glands. Lymphoma is a rare occurrence in the parotid glands and salivary glands in general, and the majority of these are non‐Hodgkin lymphoma (NHL). Hodgkin lymphoma (HL)
Daniel Dilworth, Jane Pears, Michael McDermott, Kumara Ekanayake   +3 more
wiley   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, Volume 603, Issue 15, Page 4255-4291, 1 August 2025.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

Case report: Metastatic endocrine mucin-producing sweat gland carcinoma with features of mucinous carcinoma. [PDF]

Front Oncol
Sun Y, Liu Y, Li C, Zhang X, Yin L, Niu J.   +5 more
europepmc   +1 more source

Uncommon but Not Elusive: A Case of Syringocystadenoma Papilliferum in the External Auditory Canal. [PDF]

Cureus, 2023
Shirani T, Rahim S, Ahmad Tarmizi NE, Mohan Singh AS, Hui Heng C.   +4 more
europepmc   +1 more source

Plasma hepcidin level is elevated by water immersion‐induced central fatigue via hepatic inflammatory response in male and female rats

Physiological Reports, Volume 13, Issue 15, August 2025.
Abstract Fatigue is a subjective phenomenon caused by physical or mental overexertion; however, its objective biomarkers specific to the types of fatigue remain unclear. Here, we examined whether plasma hepcidin levels, which are regulated by inflammation or iron metabolism, are elevated by peripheral and central fatigue in male and female rats.
Takuro Karaushi, Toshifumi Ogawa, Hiroyori Fusagawa, Taiki Kudo, Yuito Inoue, Takashi Yamada, Nobutoshi Ichise, Tatsuya Sato, Noritsugu Tohse   +8 more
wiley   +1 more source

A systematic review of metastatic lesions to the oral and maxillofacial regions among Japanese people. [PDF]

Jpn Dent Sci Rev
Asoda S, Yasui T, Tanaka K, Onizawa K, Kawana H, Nakagawa T.   +5 more
europepmc   +1 more source

Cancer treatment and survivorship statistics, 2025

CA: A Cancer Journal for Clinicians, Volume 75, Issue 4, Page 308-340, July/August 2025.
Abstract The number of people living with a history of cancer in the United States continues to rise because of the growth and aging of the population as well as improved survival through advances in early detection and treatment. To assist the public health community serve the needs of these survivors, the American Cancer Society and the National ...
Nikita Sandeep Wagle, Leticia Nogueira, Theresa P. Devasia, Angela B. Mariotto, K. Robin Yabroff, Farhad Islami, Ahmedin Jemal, Rick Alteri, Patricia A. Ganz, Rebecca L. Siegel   +9 more
wiley   +1 more source