Crizotinib: A Novel Strategy to Reverse Immunosuppression in Melanoma by Targeting Lactate Transport
Crizotinib inhibits CD147‐MCT1‐mediated lactate transport, suppressing melanoma growth and immune escape, prevents M2 macrophage polarization, and enhances immunotherapy by reducing CXCL13 via histone lactylation. ABSTRACT Lactate is a vital metabolite in cancer, significantly impacting tumor progression, metastasis, and overall survival.
Zhe Zhou+7 more
wiley +1 more source
Hodgkin Lymphoma of the Parotid Gland: An Unusual Presentation in a Paediatric Patient
ABSTRACT Background Malignancy involving the salivary glands is a rare occurrence; of these malignancies occurring in the salivary glands, the majority are associated with the parotid glands. Lymphoma is a rare occurrence in the parotid glands and salivary glands in general, and the majority of these are non‐Hodgkin lymphoma (NHL). Hodgkin lymphoma (HL)
Daniel Dilworth+3 more
wiley +1 more source
Sézary Syndrome—Eosinophilia Explained by a Blood Film
American Journal of Hematology, Volume 100, Issue 8, Page 1423-1424, August 2025.
Merel T. A. Soeterik+5 more
wiley +1 more source
Abstract Fatigue is a subjective phenomenon caused by physical or mental overexertion; however, its objective biomarkers specific to the types of fatigue remain unclear. Here, we examined whether plasma hepcidin levels, which are regulated by inflammation or iron metabolism, are elevated by peripheral and central fatigue in male and female rats.
Takuro Karaushi+8 more
wiley +1 more source
Eccrine malignancies in nevus sebaceus: Case presentation and review of the literature. [PDF]
Woods AD, Liu W, Krunic AL.
europepmc +1 more source
Cancer treatment and survivorship statistics, 2025
Abstract The number of people living with a history of cancer in the United States continues to rise because of the growth and aging of the population as well as improved survival through advances in early detection and treatment. To assist the public health community serve the needs of these survivors, the American Cancer Society and the National ...
Nikita Sandeep Wagle+9 more
wiley +1 more source
Benign Mixed Tumour of Eccrine Origin Presenting as Upper Lip Swelling: A Report of a Rare Case and Literature Review. [PDF]
B HK, Kumar P, Selvaraj K, Pattabi S.
europepmc +1 more source
Role of Adjuvant Radiotherapy in Sweat Gland Carcinoma: A Case Report and Literature Review. [PDF]
Bhattacharjee A+3 more
europepmc +1 more source
Clinicopathological profile of eyelid tumors at a tertiary care center: An observational prospective study. [PDF]
Prasad N+4 more
europepmc +1 more source
Hidradenocarcinoma: A rare sweat gland neoplasm presenting as small turban tumor of the scalp
DineshP Asati+3 more
openalex +1 more source