Results 171 to 180 of about 1,491,952 (305)

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Immune-checkpoint inhibitor-induced bullous pemphigoid in patients with metastatic renal cell carcinoma: two case reports and systematic review of the literature. [PDF]

Acta Oncol
Filis P, Lindskog M, Curman P, Kuzmina N, Krantz Å, Chatzidionysiou K, Costa Svedman F, Zerdes I.   +7 more
europepmc   +1 more source

TETPD in Sweden

, 2008
Information communication technology (ICT) has been bringing increasingly greater changes in education such as educational system, policies, programs, curricula, resources, teaching methods, and other aspects related to education, among which teacher ...
Gu, Limin,, Lindberg, Ola,
core  

Emergent 3D Fermiology and Magnetism in an Intercalated Van der Waals System

Advanced Science, EarlyView.
An emergent three‐dimensional electronic state is uncovered in an intercalated van der Waals system. A spin‐polarized intercalant‐host hybridized band crossing the Fermi level provides an itinerant channel for interlayer exchange, highlighting how electronic dispersion governs magnetic dimensionality.
Luigi Camerano, Emanuel A. Martínez, Victor Porée, Laura Martella, Dario Mastrippolito, Debora Pierucci, Franco D'Orazio, Polina M. Sheverdyaeva, Paolo Moras, Enrico Della Valle, Tianlun Yu, Moritz Hoesch, Craig M. Polley, Thiagarajan Balasubramanian, Alessandro Nicolaou, Luca Ottaviano, Vladimir N. Strocov, Gianni Profeta, Federico Bisti   +18 more
wiley   +1 more source

Author Correction: Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage. [PDF]

Nat Commun
Poverennaya I, Murtazina A, Li L, Maili L, Sourada L, Montano-Gutierrez LF, Galimullina R, Steinschaden T, Kaiser M, Zikmund T, Goralija A, Gao T, Attina A, Clara O, Bartenhagen C, Erickson AG, Gershtein Y, Chen S, Polaskova K, Sterba J, Semsch B, Andersson ER, Prakash V, Vincent T, Arceo M, Kogner P, Schlisio S, Kharchenko PV, David A, Kaiser J, Fischer M, Skoda J, Trainor PA, Chagin AS, Adameyko I.   +34 more
europepmc   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Isolated, reduced diffusing capacity for carbon monoxide in the population - relations to symptoms, smoking and comorbidities. [PDF]

BMC Pulm Med
Hamrefors V, Westerbergh J, Behndig A, Blomberg A, Brandberg J, Carlén A, Egesten A, Ekbom E, Emilsson ÖI, Eriksson MJ, Frølich A, Grote L, Janson C, Karimi R, Moberg A, Persson HL, Pesonen I, Sköld M, Sörensen K, Tanash H, Torén K, Vanfleteren L, Wollmer P, Malinovschi A.   +23 more
europepmc   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Prescription Medication Use During Pregnancy and Postpartum in Sweden 2007 to 2022. [PDF]

Pharmacoepidemiol Drug Saf
Heinonen EW, Smew AI, Chacón SS, Nörby U, Stephansson O, Örtqvist AK, Axfors C, Karlsson P, Cesta CE.   +8 more
europepmc   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source