Results 41 to 50 of about 91,551 (149)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Clinical Ophthalmology, 2021 Andreas G Nilsson,1 Dorothea Peters2 1Department of Ophthalmology, Skåne University Hospital, Malmö, Sweden; 2Department of Clinical Sciences Malmö, Ophthalmology, Lund University, Malmö, SwedenCorrespondence: Andreas G Nilsson Email andreas.g.nilsson ...
Nilsson AG, Peters D
doaj
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Prospects for the UK Cooperation with the Scandinavian-Baltic States after Brexit
Международная аналитика, 2019 The article is devoted to analyzing various aspects of the impact of Brexit consequences on the states of the Scandinavian-Baltic region and the prospects for relations with them.
V. V. Vorotnikov
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Implementation features of large economic models
π-Economy, 2023 Agent-based economic models are invaluable tools for understanding complex economic systems and informed political decisions. However, the computational demands of large-scale agent-based models often require significant resources, limiting their ...
Bragin Aleksey, Bakhtizin Albert
doaj +1 more source
Molecular Oncology, EarlyView.The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Knockaloe Kampında Bir Osmanlı Diplomatı: Reşid Sadi Bey’in Esareti (1915-1918)
Akademik İncelemeler Dergisi, 2017 I. DünyaSavaşı’nın başlaması üzerine İngiltere, ülkesinde bulunan Müttefik Devletler’invatandaşlarını tutuklamaya başlamış, ardından da bunları sivil esir olarakçeşitli yerlere sevk etmişti.
Evren Küçük
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CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source