Results 101 to 110 of about 38,345 (264)
British Journal of Clinical Pharmacology, EarlyView.Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding +6 more
wiley +1 more source
Translation, Evaluation and Validation of the Adult Strabismus −20 (AS-20) Questionnaire in Swedish
Clinical OphthalmologyLena Havstam Johansson,1,2 Anna Levinsson,3,4 Sara M Flodin1,2 1Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 2Department of Ophthalmology, Sahlgrenska ...
Havstam Johansson L +2 more
doaj
Prescribing variation across Europe: Insights into prescribing practices and educational needs
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing medication is a complex process, influenced by many factors that can be weighed differently. Four prescriber profiles have been identified: pragmatic‐contextual, guideline‐oriented, experience‐driven and vulnerability‐focused. However, the extent to which European prescribers identify with these profiles and the role of these profiles ...
Mariëlle G. Hartjes +3 more
wiley +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić +8 more
wiley +1 more source
Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study
British Journal of Clinical Pharmacology, EarlyView.Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae +6 more
wiley +1 more source
Journal of Pain Research, 2019 Karin Asztély,1 Svenny Kopp,2 Christopher Gillberg,2 Margda Waern,3 Stefan Bergman1 1Department of Public Health and Community Medicine, Sahlgrenska Academy Institute of Medicine, Göteborg, Sweden; 2Gillberg Neuropsychiatric Centre ...
Asztély K +4 more
doaj
Listening to Hong Kong children's perspectives through pretend play
British Educational Research Journal, EarlyView.Abstract Quality in early childhood education and care (ECEC) has become an increasing concern in recent years. The issue has been regularly discussed by different stakeholders. However, the rising concern regarding quality in ECEC has not seriously taken into account children's perspectives.
Suzannie K. Y. Leung
wiley +1 more source