Metastatic renal cell carcinoma: risk of rapid progression to pathological fractures and factors influencing post-treatment survival - a Swedish Nationwide cohort study. [PDF]
Åkerstedt J +3 more
europepmc +1 more source
Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations
Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl +7 more
wiley +1 more source
Biochemical osteomalacia during pregnancy or lactation: an observational study in Sweden. [PDF]
Torstensson T +2 more
europepmc +1 more source
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin +25 more
wiley +1 more source
Explaining the Slow Adoption of AI Innovations in Health Care: Network Analysis Approach. [PDF]
Apell P, Locher S, Milde A, Eriksson H.
europepmc +1 more source
Swedish Children’s Literature Today
openaire +2 more sources
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
What do they say they are doing? a mixed-methods analysis of Swedish gambling operators' duty of care action plans. [PDF]
Lakew N, Lindner P.
europepmc +1 more source
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu +13 more
wiley +1 more source
A national-scale dataset of arable plant abundance from citizen science surveys of swedish field margins. [PDF]
Örnberg RC +8 more
europepmc +1 more source

