CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
A sensorimotor instability drives a locomotor transition during fish development. [PDF]
Coraggioso M +9 more
europepmc +1 more source
Present Studies on Modern Swimming(Fin Swimming and Underwater Swimming)in Japan
T, Nomura, Y, Matsuzaki
openaire +3 more sources
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Swimming exercise during early-life starvation enhances adult stress resistance in <i>Caenorhabditis elegans</i>. [PDF]
Zayas-Feliciano NS, Ramos-Ortolaza DL.
europepmc +1 more source
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Enhanced bacterial chemotaxis in confined microchannels occurs at lane widths matching circular swimming radius. [PDF]
Yue C, Zhang C, Zhang R, Yuan J.
europepmc +1 more source
Exploring the Swimming and Water Safety Behaviour Among Indian and Vietnamese Adults in Australia. [PDF]
Low L +3 more
europepmc +1 more source
Heart rate and activity patterns of chinook salmon (Oncorhynchus tshawytscha) under steady and unsteady flow conditions. [PDF]
Agbeti WEK +3 more
europepmc +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source

