Results 241 to 250 of about 226,726 (304)

Decoding the Hexosamine Biosynthesis Pathway: Implications for Novel Therapeutic Strategies in Sarcoma

open access: yesJournal of Cellular Physiology, Volume 241, Issue 5, May 2026.
ABSTRACT Cancer cells rewire their metabolism to sustain a high proliferation rate. Sensing external cues is essential to match the metabolic fluxes of the cells to the external stimuli. As part of the glucose metabolism, the hexosamine biosynthesis pathway (HBP) is considered a nutrient‐sensing pathway. The HBP produces UDP‐GlcNAc, a key precursor for
Pegah Rahimizadeh   +4 more
wiley   +1 more source

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay   +2 more
wiley   +1 more source

Suppression of Calcium Influx Reduces Coxsackievirus B3 Lethality With Elevated Interferon Beta Responses in Mice

open access: yesJournal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT The disease course of severe enterovirus (EV) infection with hepatic necrosis is usually fulminant and fatal. Coxsackievirus (CVB3) is the emerging and important serotype of newborn EV inducing hepatic necrosis. Calcium (Ca2+) regulates host immunity, type I interferon (IFN‐I), and viral infections.
Yi‐Ling Hsiao   +3 more
wiley   +1 more source

Determination of digestible indispensable amino acid score for salmon hydrolysate proteins

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 7, Page 4295-4301, May 2026.
Abstract BACKGROUND Salmon products are excellent foods that contain indispensable nutrients including fatty acids and amino acids (AA), but during processing, salmon co‐products that cannot be used for the primary purpose are also generated. Examples of such co‐products include salmon protein hydrolysate concentrate (SPHC) and salmon protein ...
Natalia S Fanelli   +2 more
wiley   +1 more source

Wild pig habitat use impacted by prescribed fire in the William B. Bankhead National Forest, USA

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 4, May 2026.
Natural resource management activities like integrated wild pig control programs and 3–5‐year interval prescribed burning can reduce wild pig activity and habitat but can have an unintended side effect of allowing them to thrive in sensitive and protected areas, where access and tools are restricted.
Patience E. Knight   +2 more
wiley   +1 more source

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