Results 171 to 180 of about 7,612 (306)

Hypersonic research engine project. Phase 2: Some combustor test results of NASA aerothermodynamic integration model [PDF]

Combustor test results of the NASA Aerothermodynamic Integration Model are presented of a ramjet engine developed for operation between Mach 3 and 8.
Gaede, A. E., Sainio, W. C., Sun, Y. H.
core   +1 more source

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

Advanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen, Yang Zhao, Boqiang Hu, Wuke Wang, Minfang Song, Annabeth Xinyu Zhao, Xiangyang Li, Gefei Wang, Yanfen Wang, Weiyan Zheng, Xinpeng Zhang, Xia Lin, Yanbin Yin, Xingxu Huang, Jinfang Zheng, Tingbo Liang   +15 more
wiley   +1 more source

Experimental Study of Flame Dynamics in a Triple-Injector Swirling Nonpremixed Combustor Under Different Thermoacoustic Self-Excited Instability Modes. [PDF]

Sensors (Basel)
Zhang X, Wang S, Liu Y.
europepmc   +1 more source

Spray Development of E85 and Gasoline in a Quiescent Chamber and in a Direct-Injection Spark-Ignition Engine [PDF]

, 2008
Aleiferis, PG, Caine, J, Serras-Pereira, J, Van Romunde, ZR   +3 more
core  

Experimental and analytical investigation of the variation of spray characteristics along a radial distance downstream of a pressure-swirl atomizer [PDF]

The variation of spray characteristics along a radial distance downstream of a pressure-swirl atomizer was measured by laser light-scattering technology. An analytical model was developed to predict the variation of spray characteristics along the radial
Chin, J. S., Li, W. M., Wang, X. F.
core   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Instrumentation Strategies for Monitoring Flow in Centrifugal Compressor Diffusers: Techniques and Case Studies. [PDF]

Sensors (Basel)
Prisăcariu EG, Dumitrescu O.
europepmc   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Optimization strut-based fuel injection using multi-step hydrogen jets and air-assisted mixing in supersonic flow. [PDF]

Sci Rep
Houria ZB, Hajlaoui K, Aminian SA, Musa VA, Sadeq AM, Shaban M, Aich W, Kriaa K.   +7 more
europepmc   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source