Results 131 to 140 of about 706,905 (339)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

A System to Ensure Safety while Switching High Voltage Switchgears

, 2022
Switchgears, Prashobh Karunakaran, M Osman, Prashanth Karunakaran, Shanthi Karunakaran, Arjun Karunakaran, Kwong Ting, Alexon John, S Park, Prashobh Karunakaran, ; Mohammad, Shahril Osman, Ian Rino, Anak Boniface, ; Atif, Norzan Shah, P Karunakaran, T Hazel, G Robb, P Karunakaran, M Osman, P Karunakaran, S Karunakaran, A Karunakaran, M Lee, A John, G Diendorfer, W Schulz, V Rakov, Prashobh; Karunakaran, M Osman, V Karuppanna, S Cheng, M Lee, A John, T Hieng, S Yokoyama, K Miyake, T Suzuki, S Kanao, L Campbell, Prashobh; Karunakaran, M Osman, V Karuppanna, S Cheng, L Djun, A John, T Hieng, D Koch, Prashobh Karunakaran, ; Mohd, Shahril Osman; Alvin, K Lau; Man, Djun Lee, ; Pradeep Kumar, S Skinner, J Kilner, Prashobh; Karunakaran, M Osman, V Karuppanna, S Cheng, M Lee, A Richard, A Lau, C Dervos, P Vassiliou, J Mergos, B Bui, N Uchiyama, K Simba, E Petkov, V Angelov, Alexander Jacobsen, Jardim, P Tore Rein, J Haveland, Rykkje, T Impelluso, T, N Doerry, J Amy, A Rankin, J Rengifo, J Romero, J Aller, R Lee, N Mutyam, T Saikumar, B Soppari   +88 more
openalex   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

ANOMALY DETECTION OF NETWORK SWITCHES PERFORMANCE IN I&C SYSTEM BASED ON NETWORK CALCULUS

, 2023
Zijian Wu, Jianghai Li, Shuqiao Zhou, Xiaojin Huang   +3 more
openalex   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Analysis of exponential stability and L1-gain performance of positive switched impulsive systems with all unstable subsystems

Nonlinear Analysis
This article investigates the exponential stability and L1-gain performance of time-varying positive switched impulsive systems even when all modes are unstable.
Xiukun Zhang, Yuangong Sun, Xingao Zhu
doaj   +1 more source

Certifying Unstability of Switched Systems Using Sum of Squares Programming

, 2020
Benoît Legat, Pablo A. Parrilo, Raphaël M. Jungers   +2 more
openalex   +2 more sources

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Stabilization of saturated switching systems [PDF]

, 2009
In this chapter, two directions are explored: the first concerns the synthesis of non saturating controllers, while the second direction deals with controllers tolerating saturations to take effect. The second method was firstly used in [22] with the use of a multiple Lyapunov function. However, only the intersection of all the corresponding level sets
openaire   +2 more sources

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source