Results 71 to 80 of about 320,578 (269)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Kalman Filter-Based Localization Calibration Method Optimized by Reinforcement Learning and Information Matrix Fusion

Entropy
To address the degradation in localization accuracy caused by insufficient robustness of filter parameters and inefficient multi-trajectory data fusion in dynamic environments, this paper proposes a Kalman filter-based localization calibration method ...
Zijia Huang, Qiushi Xu, Menghao Sun, Xuzhen Zhu   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

High-Precision Time Delay Estimation Algorithm Based on Generalized Quadratic Cross-Correlation

Mathematics
In UAV target localization, the accuracy of time delay estimation is the key to high-precision positioning. However, under low signal-to-noise ratio (SNR), time delay estimation suffers from serious secondary peak interference and low accuracy, which ...
Menghao Sun, Ziang Niu, Xuzhen Zhu, Zijia Huang   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

CPS-LSTM: Privacy-Sensitive Entity Adaptive Recognition Model for Power Systems

Energies
With the widespread application of Android devices in the energy sector, an increasing number of applications rely on SDKs to access privacy-sensitive data, such as device identifiers, location information, energy consumption, and user behavior. However,
Hao Zhang, Jing Wang, Xuanyuan Wang, Xuhui Lü, Zhenzhi Guan, Zhenghua Cai, Hua Zhang   +6 more
doaj   +1 more source

Switching control

Journal of the European Mathematical Society, 2010
We analyze the problem of switching controls for control systems endowed with different actuators. The goal is to control the dynamics of the system by switching from an actuator to the other in a systematic way so that, in each instant of time, only one actuator is active. We first address a finite-dimensional model and show that,
openaire   +3 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Stabilizing a memristor-based chaotic system by switching control and fuzzy modeling

上海师范大学学报. 自然科学版, 2016
We investigate the stabilization of a memristor-based chaotic system.Based on the system,a T-S model is established and a switching controller is designed.Then,by Lyapunov stability theory,one can acquire a criterion to guarantee that the conclusion ...
MA Fuling, XING Dahong
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source