Results 51 to 60 of about 364,806 (252)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Digitally Controlled Power LEDs Switching Power Supply [PDF]

open access: yes, 2017
Tato práce se zabývá teorií napájecích proudových zdrojů v elektronice. V úvodu práce je základní porovnání lineárních a spínaných zdrojů z hlediska funkce a elektrických parametrů. Dále v práci jsou zejména popisovány zdroje spínané.
Nosek Jan
core  

Design and analysis of a high-efficiencyv high-voltage class-D power output stage [PDF]

open access: yes, 2014
The analysis and design of a highly-efficient 80 V class-D power stage design in a 0.14 μm SOI-based BCD process is described. It features immunity to the on-chip supply bounce, realized by internally regulated floating supplies, variable driving ...
Ma, Haifeng   +2 more
core   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Linear-assisted DC/DC converters with modified current-mode control applied to photovoltaic solar systems [PDF]

open access: yes, 2014
This article shows the proposal of a current-mode one-cycle control for linear-assisted DC/DC converters. Linearassisted DC/DC converters are structures that allow to take advantages of the two classic alternatives in the design of power supply systems ...
Martínez García, Herminio
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Application of Digital Control Technology in Intrinsic Safety Switching Power Supply

open access: yesGong-kuang zidonghua, 2010
In order to solve problems of small output power, low working frequency, large output ripple and high fault rate, the paper proposed a design scheme of applying DSPIC30F1010/2020 digital control chip in intrinsic safety switching power supply, gave the ...
YIN Xiang-qing   +3 more
doaj  

Multi-port Bidirectional Energy Router for Urban Rail Transit and Its Key Technologies

open access: yesKongzhi Yu Xinxi Jishu, 2022
At present, urban rail transit power supply system can only realize unidirectional power supply, which cannot meet the development needs of green, intelligent and interconnected energy internet.
SU Liangliang   +5 more
doaj   +1 more source

Remotely-actuated biomedical switch [PDF]

open access: yes, 1969
Remotely-actuated biomedical switching circuit using transistors consumes no power in the off position and can be actuated by a single-frequency telemetry pulse to control implanted instrumentation. Silicon controlled rectifiers permit the circuit design
Lee, R. D.
core   +1 more source

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