Results 21 to 30 of about 8,565 (201)
The article explores the problem of preconditions for taking free and independent decision by a person committing suicide. Furthermore, it answers the question how the process of taking free decision by a person committing suicide influences the criminal
Julia Kosonoga-Zygmunt
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Highlights • NURTURE is an ongoing study of nusinersen started in a presymptomatic stage of SMA.• All infants were ≥25 months old, and alive without permanent ventilation.• All infants achieved independent sitting and 88% (22/25) were walking alone ...
D. D. De Vivo +28 more
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Results from a phase 1 study of nusinersen (ISIS-SMNRx) in children with spinal muscular atrophy
Objective: To examine safety, tolerability, pharmacokinetics, and preliminary clinical efficacy of intrathecal nusinersen (previously ISIS-SMNRx), an antisense oligonucleotide designed to alter splicing of SMN2 mRNA, in patients with childhood spinal ...
C. Chiriboga +8 more
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Most children with biallelic SMN1 deletions and three SMN2 copies develop spinal muscular atrophy (SMA) type 2. SPR1NT (NCT03505099), a Phase III, multicenter, single-arm trial, investigated the efficacy and safety of onasemnogene abeparvovec for ...
K. Strauss +20 more
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NURTURE (NCT02386553) is an open‐label study of nusinersen in children (two SMN2 copies, n = 15; three SMN2 copies, n = 10) who initiated treatment in the presymptomatic stage of spinal muscular atrophy (SMA).
T. Crawford +24 more
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SWOBODA MIE˛DZYNARODOWEGO ŚWIADCZENIA USŁUG BANKOWYCH W UNII EUROPEJSKIEJ
Ze względu na procesy globalizacji i integracji europejskiej bankowość się internacjonalizuje, to znaczy świadczenie usług bankowych odbywa się na międzynarodową skalę.
Michał Kruszka
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The introduced article is composed of four parts. The first concerns the general principles relating to the education of man. The second part says about persons responsible for upbringing of the child, especially about the role of parents. In the third
Antoni Swoboda
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Wizerunek matki w pismach Seneki filozofa i w "Enarrationes in psalmos" św. Augustyna
L'articolo e stato diviso in tre parti. Nella prima parte sono stati presentati gli interventi dei entrambi autori a proposito delle qualita negative, le quali dovrebbe evitare la madre, per es.: perenne iagnanze, invidia, vanita, esagerata ...
Antoni Swoboda
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Piecza zastępcza jako element systemu pomocy rodzinie – na przykładzie gminy Poznań
The text brings together the legal basis and assumptions of foster care. This is an institution regulated under Polish law by the Act of 9 June 2011 on Family Support and the Foster Care System (consolidated text Journal of Laws of 2025, item 49 ...
Joanna Zaremba-Stanulewicz
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Zniewalająca siła ekfrazy (rzecz o zmaganiach słowa i obrazu w poglądach W.J.T. Mitchella)
The article – in its first part titled The space of theory – brings a discussion and interpretation of the theoretical views concerning ekphrasis formulated by W.J.T. Mitchell in the essay Ekphrasis and the Other.
Bartosz Swoboda
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