Results 171 to 180 of about 178,622 (348)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Cognitive Resilience Education in the Czech Military: SWOT Analysis [PDF]
This article presents the first systematic analysis of cognitive resilience education within the Czech Ministry of Defence, which is growing in importance in the context of contemporary hybrid threats.
Vendula Divišová +3 more
core +1 more source
SWOT Analysis of Health Reform Plan on Healthcare Sector from the Stakeholder Perspective
Journal of Mazandaran University of Medical Sciences, 2018 Background and purpose: Today, health is one of the main priorities of human life. Nowadays, the viewpoints about health are different and more attention is paid to nonmedical expectations.
Ghasem Abedi +5 more
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
From SOFT approach to SWOT analysis, a historical reconstruction
Journal of Management HistoryPurpose The purpose of this study is to revisit the conventional wisdom about a key contribution [i.e. strengths, weaknesses, opportunities, threats (SWOT) analysis] in the field of strategic management.
R. Puyt, Finn Birger Lie, D. Madsen
semanticscholar +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
FaSt-SWOT - De l'espai al Mediterrani: estudiant corrents marins [PDF]
Disponible en castellano, catalán e inglés.La infografía ’Del espacio al Mediterráneo: persiguiendo corrientes marinas’ forma parte del proyecto científico FaSt-SWOT(Corrientes oceánicas de pequeña escala a partir de experimentos integrados ...
Bonilla, Ana +8 more
core +1 more source
Fine-Scale Eddies Detected by SWOT in the Kuroshio Extension
Remote SensingConventional altimetry has greatly advanced our understanding of mesoscale eddies but falls short in studying fine-scale eddies (
Tianshi Du, Zhao Jing
semanticscholar +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source